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Abstract

We evaluated neutralising antibody titres against wild type (WT) SARS-CoV-2 and four Omicron variants (BA.1, BA.2, BA.5 and BA.2.75) in fully vaccinated (three doses of Comirnaty vaccine) healthcare workers (HCW) in Israel who had breakthrough BA.1/BA5 infections. Omicron breakthrough infections in vaccinated individuals resulted in increased neutralising antibodies against the WT and Omicron variants compared with vaccinated uninfected HCW. HCW who recovered from BA.1 or BA.5 infections showed similar neutralising antibodies levels against BA.2.75.

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/content/10.2807/1560-7917.ES.2022.27.44.2200785
2022-11-03
2024-12-21
/content/10.2807/1560-7917.ES.2022.27.44.2200785
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Omicron BA.2.75 variant is efficiently neutralised following BA.1 and BA.5 breakthrough infection in vaccinated individuals, Israel, June to September 2022
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Nofar+Atari&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Atari Nofar</a>, <a href="/search?value1=Limor+Kliker&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kliker Limor</a>, <a href="/search?value1=Neta+Zuckerman&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zuckerman Neta</a>, <a href="/search?value1=Bayan+Abd+Elkader&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Elkader Bayan Abd</a>, <a href="/search?value1=Yael+Weiss-Ottolenghi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Weiss-Ottolenghi Yael</a>, <a href="/search?value1=Ella+Mendelson&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mendelson Ella</a>, <a href="/search?value1=Yitshak+Kreiss&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kreiss Yitshak</a>, <a href="/search?value1=Gili+Regev-Yochay&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Regev-Yochay Gili</a>, <a href="/search?value1=Michal+Mandelboim&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mandelboim Michal</a></span>. Omicron BA.2.75 variant is efficiently neutralised following BA.1 and BA.5 breakthrough infection in vaccinated individuals, Israel, June to September 2022 . <a href="/content/ecdc">Euro Surveill.</a> 2022;27(44):pii=2200785. <a href="https://doi.org/10.2807/1560-7917.ES.2022.27.44.2200785" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2022.27.44.2200785</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 06 Oct 2022;&nbsp;&nbsp; <span class="generated">Accepted</span>: 02 Nov 2022 </span> </p>
/content/10.2807/1560-7917.ES.2022.27.44.2200785
/content/10.2807/1560-7917.ES.2022.27.44.2200785
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