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Abstract

A monkeypox virus (MPXV) outbreak has been ongoing worldwide since May 2022. The role of specimens other than skin lesions for MPXV diagnosis is unknown. We evaluated 140 different clinical specimens by real-time PCR. The highest positivity rates (97%) were from skin lesions of any part of the body, followed by plasma, pharyngeal and anal swabs. Testing specimens from multiple sites may improve the sensitivity and reduce false-negative test results.

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/content/10.2807/1560-7917.ES.2022.27.33.2200598
2022-08-18
2024-11-21
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2022.27.33.2200598
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References

  1. Peiró-Mestres A, Fuertes I, Camprubí-Ferrer D, Marcos , Vilella A, Navarro M, et al. Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022. Euro Surveill. 2022;27(28).  https://doi.org/10.2807/1560-7917.ES.2022.27.28.2200503  PMID: 35837964 
  2. Iñigo Martínez J, Gil Montalbán E, Jiménez Bueno S, Martín Martínez F, Nieto Juliá A, Sánchez Díaz J, et al. Monkeypox outbreak predominantly affecting men who have sex with men, Madrid, Spain, 26 April to 16 June 2022. Euro Surveill. 2022;27(27):2200471.  https://doi.org/10.2807/1560-7917.ES.2022.27.27.2200471  PMID: 35801519 
  3. Kraemer MUG, Tegally H, Pigott DM, Dasgupta A, Sheldon J, Wilkinson E, et al. Tracking the 2022 monkeypox outbreak with epidemiological data in real-time. Lancet Infect Dis. 2022;22(7):941-2.  https://doi.org/10.1016/S1473-3099(22)00359-0  PMID: 35690074 
  4. Isidr J, Borges V, Pinto M, Ferreira R, Sobral D, Nunes A, et al. Multi-country outbreak of Monkeypox virus: genetic divergence and first signs of microevolution. Available from: https://virological.org/t/multi-country-outbreak-of-monkeypox-virus-genetic-divergence-and-first-signs-of-microevolution/806
  5. Buenestado S, Palomino R, Peñas D, Herranz M, Cobos A, Ventimilla C, et al. Update: Two draft genomes from Madrid, Spain, of the Monkeypox virus 2022 outbreak. Virological.org. 8 Jun 2022. Available from: https://virological.org/t/updatetwo-draft-genomes-from-madrid-spain-of-the-monkeypoxvirus-2022-outbreak/848
  6. Noe S, Zange S, Seilmaier M, Antwerpen MH, Fenzl T, Schneider J, et al. Clinical and virological features of first human monkeypox cases in Germany. Infection. 2022;1-6.  https://doi.org/10.1007/s15010-022-01874-z  PMID: 35816222 
  7. Antinori A, Mazzotta V, Vita S, Carletti F, Tacconi D, Lapini LE, et al. Epidemiological, clinical and virological characteristics of four cases of monkeypox support transmission through sexual contact, Italy, May 2022. Euro Surveill. 2022;27(22):2200421.  https://doi.org/10.2807/1560-7917.ES.2022.27.22.2200421  PMID: 35656836 
  8. Tarín-Vicente EJ, Alemany A, Agud-Dios M, Ubals M, Suñer C, Antón A, et al. Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study. Lancet Infect Dis. 2022.
  9. Thornhill JP, Barkati S, Walmsley S, Rockstroh J, Antinori A, Harrison LB, et al. Monkeypox virus infection in humans across 16 countries - April-June 2022. N Engl J Med. 2022;NEJMoa2207323.  https://doi.org/10.1056/NEJMoa2207323  PMID: 35866746 
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