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Abstract

A monkeypox virus (MPXV) outbreak has been ongoing worldwide since May 2022. The role of specimens other than skin lesions for MPXV diagnosis is unknown. We evaluated 140 different clinical specimens by real-time PCR. The highest positivity rates (97%) were from skin lesions of any part of the body, followed by plasma, pharyngeal and anal swabs. Testing specimens from multiple sites may improve the sensitivity and reduce false-negative test results.

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/content/10.2807/1560-7917.ES.2022.27.33.2200598
2022-08-18
2024-12-22
/content/10.2807/1560-7917.ES.2022.27.33.2200598
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The relevance of multiple clinical specimens in the diagnosis of monkeypox virus, Spain, June 2022
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Cristina+Veintimilla&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Veintimilla Cristina</a>, <a href="/search?value1=Pilar+Catal%C3%A1n&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Catalán Pilar</a>, <a href="/search?value1=Roberto+Alonso&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Alonso Roberto</a>, <a href="/search?value1=Dar%C3%ADo+Garc%C3%ADa+de+Viedma&option1=author&noRedirect=true" class="nonDisambigAuthorLink">García de Viedma Darío</a>, <a href="/search?value1=Laura+P%C3%A9rez-Lago&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pérez-Lago Laura</a>, <a href="/search?value1=Mar%C3%ADa+Palomo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Palomo María</a>, <a href="/search?value1=Alejandro+Cobos&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cobos Alejandro</a>, <a href="/search?value1=Teresa+Aldamiz-Echevarria&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Aldamiz-Echevarria Teresa</a>, <a href="/search?value1=Patricia+Mu%C3%B1oz&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Muñoz Patricia</a></span>. The relevance of multiple clinical specimens in the diagnosis of monkeypox virus, Spain, June 2022. <a href="/content/ecdc">Euro Surveill.</a> 2022;27(33):pii=2200598. <a href="https://doi.org/10.2807/1560-7917.ES.2022.27.33.2200598" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2022.27.33.2200598</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 25 Jul 2022;&nbsp;&nbsp; <span class="generated">Accepted</span>: 11 Aug 2022 </span> </p>
/content/10.2807/1560-7917.ES.2022.27.33.2200598
/content/10.2807/1560-7917.ES.2022.27.33.2200598
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