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Abstract

Background

Non-pharmaceutical interventions (NPIs) were implemented worldwide to control the spread of SARS-CoV-2.

Aim

To evaluate the impact of tiered NPIs and a nationwide lockdown on reduction of COVID-19 incidence during the second and third epidemic waves in Portugal.

Methods

Surveillance data on laboratory-confirmed COVID-19 cases were used to conduct an interrupted time series analysis to estimate changes in daily incidence during a second wave tiered NPI period (9 November–18 December 2020), and a third wave lockdown period without (15–21 January 2021) and with school closure (22 January–10 February 2021).

Results

Significant changes in trends were observed for the overall incidence rate; declining trends were observed for tiered NPIs (−1.9% per day; incidence rate ratio (IRR): 0.981; 95% confidence interval (CI): 0.973–0.989) and a lockdown period without (−3.4% per day; IRR: 0.966; 95% CI: 0.935–0.998) and with school closure (−10.3% per day, IRR: 0.897; 95% CI: 0.846–0.951). Absolute effects associated with tiered NPIs and a lockdown on a subsequent 14-day period yielded 137 cases and 437 cases per 100,000 population potentially averted, respectively.

Conclusion

Our results indicate that tiered NPIs implemented during the second wave caused a decline in COVID-19 incidence, although modest. Moreover, a third wave lockdown without school closure was effective in reducing COVID-19 incidence, but the addition of school closure provided the strongest effect. These findings emphasise the importance of early and assertive decision-making to control the pandemic.

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This work is licensed under a Creative Commons Attribution 4.0 International License.
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/content/10.2807/1560-7917.ES.2022.27.23.2100497
2022-06-09
2024-11-24
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2022.27.23.2100497
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Impact of stringent non-pharmaceutical interventions applied during the second and third COVID-19 epidemic waves in Portugal, 9 November 2020 to 10 February 2021: an ecological study
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Ana+Rita+Torres&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Torres Ana Rita</a>, <a href="/search?value1=Ana+Paula+Rodrigues&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rodrigues Ana Paula</a>, <a href="/search?value1=Mafalda+Sousa-Uva&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sousa-Uva Mafalda</a>, <a href="/search?value1=Irina+Kislaya&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kislaya Irina</a>, <a href="/search?value1=Susana+Silva&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Silva Susana</a>, <a href="/search?value1=Liliana+Antunes&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Antunes Liliana</a>, <a href="/search?value1=Carlos+Dias&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Dias Carlos</a>, <a href="/search?value1=Baltazar+Nunes&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nunes Baltazar</a></span>. Impact of stringent non-pharmaceutical interventions applied during the second and third COVID-19 epidemic waves in Portugal, 9 November 2020 to 10 February 2021: an ecological study. <a href="/content/ecdc">Euro Surveill.</a> 2022;27(23):pii=2100497. <a href="https://doi.org/10.2807/1560-7917.ES.2022.27.23.2100497" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2022.27.23.2100497</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 21 Mar 2021;&nbsp;&nbsp; <span class="generated">Accepted</span>: 21 Jan 2022 </span> </p>
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