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Abstract

German national surveillance data analysis shows that hospitalisation odds associated with Omicron lineage BA.1 or BA.2 infections are up to 80% lower than with Delta infection, primarily in ≥ 35-year-olds. Hospitalised vaccinated Omicron cases’ proportions (2.3% for both lineages) seemed lower than those of the unvaccinated (4.4% for both lineages). Independent of vaccination status, the hospitalisation frequency among cases with Delta seemed nearly threefold higher (8.3%) than with Omicron (3.0% for both lineages), suggesting that Omicron inherently causes less severe disease.

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/content/10.2807/1560-7917.ES.2022.27.22.2200396
2022-06-02
2024-11-21
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2022.27.22.2200396
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SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Claudia+Sievers&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sievers Claudia</a>, <a href="/search?value1=Benedikt+Zacher&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zacher Benedikt</a>, <a href="/search?value1=Alexander+Ullrich&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ullrich Alexander</a>, <a href="/search?value1=Matthew+Huska&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Huska Matthew</a>, <a href="/search?value1=Stephan+Fuchs&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fuchs Stephan</a>, <a href="/search?value1=Silke+Buda&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Buda Silke</a>, <a href="/search?value1=Walter+Haas&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Haas Walter</a>, <a href="/search?value1=Michaela+Diercke&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Diercke Michaela</a>, <a href="/search?value1=Matthias+an+der+Heiden&option1=author&noRedirect=true" class="nonDisambigAuthorLink">an der Heiden Matthias</a>, <a href="/search?value1=Stefan+Kr%C3%B6ger&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kröger Stefan</a></span>. SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022. <a href="/content/ecdc">Euro Surveill.</a> 2022;27(22):pii=2200396. <a href="https://doi.org/10.2807/1560-7917.ES.2022.27.22.2200396" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2022.27.22.2200396</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 17 May 2022;&nbsp;&nbsp; <span class="generated">Accepted</span>: 02 Jun 2022 </span> </p>
/content/10.2807/1560-7917.ES.2022.27.22.2200396
/content/10.2807/1560-7917.ES.2022.27.22.2200396
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