1887
  1. Home
  2. Eurosurveillance
  3. Volume 27, Issue 13, 31/Mar/2022
  4. Article
Rapid communication Open Access
Like 0
Download

Abstract

Since the first reports in summer 2020, SARS-CoV-2 reinfections have raised concerns about the immunogenicity of the virus, which will affect SARS-CoV-2 epidemiology and possibly the burden of COVID-19 on our societies in the future. This study provides data on the frequency and characteristics of possible reinfections, using the French national COVID-19 testing database. The Omicron variant had a large impact on the frequency of possible reinfections in France, which represented 3.8% of all confirmed COVID-19 cases since December 2021.

© Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2022.27.13.2200247
2022-03-31
2024-12-22
/content/10.2807/1560-7917.ES.2022.27.13.2200247
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/27/13/eurosurv-27-13-1.html?itemId=/content/10.2807/1560-7917.ES.2022.27.13.2200247&mimeType=html&fmt=ahah

References

  1. Altarawneh HN, Chemaitelly H, Hasan MR, Ayoub HH, Qassim S, AlMukdad S, et al. Protection against the Omicron variant from previous SARS-CoV-2 infection. N Engl J Med. 2022;NEJMc2200133.  https://doi.org/10.1056/NEJMc2200133  PMID: 35139269 
  2. Eggink D, Andeweg SP, Vennema H, van Maarseveen N, Vermaas K, Vlaemynck B, et al. Increased risk of infection with SARS-CoV-2 Omicron BA.1 compared with Delta in vaccinated and previously infected individuals, the Netherlands, 22 November 2021 to 19 January 2022. Euro Surveill. 2022;27(4):2101196.  https://doi.org/10.2807/1560-7917.ES.2022.27.4.2101196  PMID: 35086609 
  3. Kuhlmann C, Mayer CK, Claassen M, Maponga T, Burgers WA, Keeton R, et al. Breakthrough infections with SARS-CoV-2 omicron despite mRNA vaccine booster dose. Lancet. 2022;399(10325):625-6.  https://doi.org/10.1016/S0140-6736(22)00090-3  PMID: 35063123 
  4. World Health Organization (WHO). Weekly epidemiological update on COVID-19 - 22 February 2022. Edition 80. Geneva: WHO; 2022. Available from: https://www.who.int/publications/m/item/weekly-epidemiological-update-on-covid-19---22-february-2022
  5. Planas D, Saunders N, Maes P, Guivel-Benhassine F, Planchais C, Buchrieser J, et al. Considerable escape of SARS-CoV-2 Omicron to antibody neutralization. Nature. 2022;602(7898):671-5.  https://doi.org/10.1038/s41586-021-04389-z  PMID: 35016199 
  6. Pulliam JRC, van Schalkwyk C, Govender N, von Gottberg A, Cohen C, Groome MJ, et al. Increased risk of SARS-CoV-2 reinfection associated with emergence of the Omicron variant in South Africa. medRxiv. 2021:2021.11.11.21266068.
  7. Cele S, Jackson L, Khoury DS, Khan K, Moyo-Gwete T, Tegally H, et al. Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization. Nature. 2022;602(7898):654-6.  https://doi.org/10.1038/s41586-021-04387-1  PMID: 35016196 
  8. European Centre for Disease Prevention and Control (ECDC). Threat Assessment Brief: Reinfection with SARS-CoV: considerations for public health response. Stockholm: ECDC; 2020. Available from: https://www.ecdc.europa.eu/en/publications-data/threat-assessment-brief-reinfection-sars-cov-2
  9. Corey L, Beyrer C, Cohen MS, Michael NL, Bedford T, Rolland M. SARS-CoV-2 variants in patients with immunosuppression. N Engl J Med. 2021;385(6):562-6.  https://doi.org/10.1056/NEJMsb2104756  PMID: 34347959 
  10. Meiring S, Tempia S, Bhiman JN, Buys A, Kleynhans J, Makhasi M, et al. Prolonged shedding of SARS-CoV-2 at high viral loads amongst hospitalised immunocompromised persons living with HIV, South Africa. Clin Infect Dis. 2022;ciac077.  https://doi.org/10.1093/cid/ciac077  PMID: 35134129 
  11. Saud Z, Ponsford M, Bentley K, Cole JM, Pandey M, Jolles S, et al. Mechanically ventilated patients shed high titre live SARS-CoV2 for extended periods from both the upper and lower respiratory tract. Clin Infect Dis. 2022;ciac170.  https://doi.org/10.1093/cid/ciac170  PMID: 35231086 
  12. Kim M-C, Cui C, Shin K-R, Bae J-Y, Kweon O-J, Lee M-K, et al. Duration of culturable SARS-CoV-2 in hospitalized patients with Covid-19. N Engl J Med. 2021;384(7):671-3.  https://doi.org/10.1056/NEJMc2027040  PMID: 33503337 
  13. Cevik M, Tate M, Lloyd O, Maraolo AE, Schafers J, Ho A. SARS-CoV-2, SARS-CoV, and MERS-CoV viral load dynamics, duration of viral shedding, and infectiousness: a systematic review and meta-analysis. Lancet Microbe. 2021;2(1):e13-22.  https://doi.org/10.1016/S2666-5247(20)30172-5  PMID: 33521734 
  14. Kissler SM, Fauver JR, Mack C, Olesen SW, Tai C, Shiue KY, et al. Viral dynamics of acute SARS-CoV-2 infection and applications to diagnostic and public health strategies. PLoS Biol. 2021;19(7):e3001333.  https://doi.org/10.1371/journal.pbio.3001333  PMID: 34252080 
  15. UK Health Security Agency (UKHSA). National flu and COVID-19 surveillance report: 3 March 2022 (week 9). London UKHSA; 2022. Available from: https://www.gov.uk/government/statistics/national-flu-and-covid-19-surveillance-reports-2021-to-2022-season
  16. Hansen CH, Michlmayr D, Gubbels SM, Mølbak K, Ethelberg S. Assessment of protection against reinfection with SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study. Lancet. 2021;397(10280):1204-12.  https://doi.org/10.1016/S0140-6736(21)00575-4  PMID: 33743221 
  17. Kojima N, Shrestha NK, Klausner JD. A systematic review of the protective effect of prior SARS-CoV-2 infection on repeat infection. Eval Health Prof. 2021;44(4):327-32.  https://doi.org/10.1177/01632787211047932  PMID: 34592838 
  18. Lo Muzio L, Ambosino M, Lo Muzio E, Quadri MFA. SARS-CoV-2 reinfection is a new challenge for the effectiveness of global vaccination campaign: a systematic review of cases reported in literature. Int J Environ Res Public Health. 2021;18(20):11001.  https://doi.org/10.3390/ijerph182011001  PMID: 34682746 
  19. Abu-Raddad LJ, Chemaitelly H, Malek JA, Ahmed AA, Mohamoud YA, Younuskunju S, et al. Assessment of the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection in an intense reexposure setting. Clin Infect Dis. 2021;73(7):e1830-40.  https://doi.org/10.1093/cid/ciaa1846  PMID: 33315061 
Impact of the Omicron variant on SARS-CoV-2 reinfections in France, March 2021 to February 2022
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Jonathan+Bastard&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bastard Jonathan</a>, <a href="/search?value1=Benjamin+Taisne&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Taisne Benjamin</a>, <a href="/search?value1=Julie+Figoni&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Figoni Julie</a>, <a href="/search?value1=Alexandra+Mailles&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mailles Alexandra</a>, <a href="/search?value1=Julien+Durand&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Durand Julien</a>, <a href="/search?value1=Myriam+Fayad&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fayad Myriam</a>, <a href="/search?value1=Laurence+Josset&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Josset Laurence</a>, <a href="/search?value1=Anna+Maisa&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Maisa Anna</a>, <a href="/search?value1=Sylvie+van+der+Werf&option1=author&noRedirect=true" class="nonDisambigAuthorLink">van der Werf Sylvie</a>, <a href="/search?value1=Isabelle+Parent+du+Ch%C3%A2telet&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Parent du Châtelet Isabelle</a>, <a href="/search?value1=Sibylle+Bernard-Stoecklin&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bernard-Stoecklin Sibylle</a></span>. Impact of the Omicron variant on SARS-CoV-2 reinfections in France, March 2021 to February 2022. <a href="/content/ecdc">Euro Surveill.</a> 2022;27(13):pii=2200247. <a href="https://doi.org/10.2807/1560-7917.ES.2022.27.13.2200247" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2022.27.13.2200247</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 17 Mar 2022;&nbsp;&nbsp; <span class="generated">Accepted</span>: 31 Mar 2022 </span> </p>
/content/10.2807/1560-7917.ES.2022.27.13.2200247
/content/10.2807/1560-7917.ES.2022.27.13.2200247
Loading

Data & Media loading...

Supplementary data

Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error