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Abstract

Following emergence of the SARS-CoV-2 variant Omicron in November 2021, the dominant BA.1 sub-lineage was replaced by the BA.2 sub-lineage in Denmark. We analysed the first 2,623 BA.2 cases from 29 November 2021 to 2 January 2022. No epidemiological or clinical differences were found between individuals infected with BA.1 versus BA.2. Phylogenetic analyses showed a geographic east-to-west transmission of BA.2 from the Capital Region with clusters expanding after the Christmas holidays. Mutational analysis shows distinct differences between BA.1 and BA.2.

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/content/10.2807/1560-7917.ES.2022.27.10.2200181
2022-03-10
2024-11-21
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2022.27.10.2200181
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Molecular epidemiology of the SARS-CoV-2 variant Omicron BA.2 sub-lineage in Denmark, 29 November 2021 to 2 January 2022
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Jannik+Fonager&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fonager Jannik</a>, <a href="/search?value1=Marc+Bennedb%C3%A6k&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bennedbæk Marc</a>, <a href="/search?value1=Peter+Bager&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bager Peter</a>, <a href="/search?value1=Jan+Wohlfahrt&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wohlfahrt Jan</a>, <a href="/search?value1=Kirsten+Maren+Ellegaard&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ellegaard Kirsten Maren</a>, <a href="/search?value1=Anna+C%C3%A4cilia+Ingham&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ingham Anna Cäcilia</a>, <a href="/search?value1=Sofie+Marie+Edslev&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Edslev Sofie Marie</a>, <a href="/search?value1=Marc+Stegger&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Stegger Marc</a>, <a href="/search?value1=Raphael+Niklaus+Sieber&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sieber Raphael Niklaus</a>, <a href="/search?value1=Ria+Lassauniere&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lassauniere Ria</a>, <a href="/search?value1=Anders+Fomsgaard&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fomsgaard Anders</a>, <a href="/search?value1=Troels+Lillebaek&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lillebaek Troels</a>, <a href="/search?value1=Christina+Wiid+Svarrer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Svarrer Christina Wiid</a>, <a href="/search?value1=Frederik+Trier+M%C3%B8ller&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Møller Frederik Trier</a>, <a href="/search?value1=Camilla+Holten+M%C3%B8ller&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Møller Camilla Holten</a>, <a href="/search?value1=Rebecca+Legarth&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Legarth Rebecca</a>, <a href="/search?value1=Thomas+Vognbjerg+Sydenham&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sydenham Thomas Vognbjerg</a>, <a href="/search?value1=Kat+Steinke&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Steinke Kat</a>, <a href="/search?value1=Sarah+Juel+Paulsen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Paulsen Sarah Juel</a>, <a href="/search?value1=Jos%C3%A9+Alfredo+Samaniego+Castruita&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Castruita José Alfredo Samaniego</a>, <a href="/search?value1=Uffe+Vest+Schneider&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Schneider Uffe Vest</a>, <a href="/search?value1=Christian+H%C3%B8jte+Schouw&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Schouw Christian Højte</a>, <a href="/search?value1=Xiaohui+Chen+Nielsen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nielsen Xiaohui Chen</a>, <a href="/search?value1=Maria+Overvad&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Overvad Maria</a>, <a href="/search?value1=Rikke+Thoft+Nielsen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nielsen Rikke Thoft</a>, <a href="/search?value1=Rasmus+L+Marvig&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Marvig Rasmus L</a>, <a href="/search?value1=Martin+Schou+Pedersen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pedersen Martin Schou</a>, <a href="/search?value1=Lene+Nielsen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nielsen Lene</a>, <a href="/search?value1=Line+Lynge+Nilsson&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nilsson Line Lynge</a>, <a href="/search?value1=Jonas+Bybjerg-Grauholm&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bybjerg-Grauholm Jonas</a>, <a href="/search?value1=Irene+Harder+Tarpgaard&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Tarpgaard Irene Harder</a>, <a href="/search?value1=Tine+Snejbjerg+Ebsen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ebsen Tine Snejbjerg</a>, <a href="/search?value1=Janni+Uyen+Hoa+Lam&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lam Janni Uyen Hoa</a>, <a href="/search?value1=Vithiagaran+Gunalan&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gunalan Vithiagaran</a>, <a href="/search?value1=Morten+Rasmussen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rasmussen Morten</a></span>. Molecular epidemiology of the SARS-CoV-2 variant Omicron BA.2 sub-lineage in Denmark, 29 November 2021 to 2 January 2022. <a href="/content/ecdc">Euro Surveill.</a> 2022;27(10):pii=2200181. <a href="https://doi.org/10.2807/1560-7917.ES.2022.27.10.2200181" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2022.27.10.2200181</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 24 Feb 2022;&nbsp;&nbsp; <span class="generated">Accepted</span>: 10 Mar 2022 </span> </p>
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