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Abstract

We assessed the impact of COVID-19 vaccination in Italy, by estimating numbers of averted COVID-19 cases, hospitalisations, ICU admissions and deaths between January and September 2021, by age group and geographical macro areas. Timing and speed of vaccination programme implementation varied slightly between geographical areas, particularly for older adults. We estimated that 445,193 (17% of expected; range: 331,059−616,054) cases, 79,152 (32%; range: 53,209−148,756) hospitalisations, 9,839 ICU admissions (29%; range: 6,434−16,276) and 22,067 (38%; range: 13,571−48,026) deaths were prevented by vaccination.

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/content/10.2807/1560-7917.ES.2021.26.47.2101001
2021-11-25
2024-12-21
/content/10.2807/1560-7917.ES.2021.26.47.2101001
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References

  1. Agenzia Italiana del Farmaco (AIFA). Vaccini COVID-19. [COVID-19 Vaccines]. Rome: AIFA. [Accessed: 1 Oct 2021]. Italian. Available from: https://www.aifa.gov.it/vaccini-covid-19
  2. Mateo-Urdiales A, Spila Alegiani S, Fabiani M, Pezzotti P, Filia A, Massari M, et al. Risk of SARS-CoV-2 infection and subsequent hospital admission and death at different time intervals since first dose of COVID-19 vaccine administration, Italy, 27 December 2020 to mid-April 2021. Euro Surveill. 2021;26(25):2100507.  https://doi.org/10.2807/1560-7917.ES.2021.26.25.2100507  PMID: 34169819 
  3. Istituto Superiore di Sanità (ISS). Epicentro. Impact of COVID-19 vaccination on the risk of SARS-CoV-2 infection and hospitalization and death in Italy (27.12.2020 - 29.08.2021). Rome: ISS; 30 Sep 2021. Italian. Available from: https://www.epicentro.iss.it/vaccini/pdf/report-valutazione-impatto-vaccinazione-covid-19-6-ott-2021.pdf
  4. Harder T, Koch J, Vygen-Bonnet S, Külper-Schiek W, Pilic A, Reda S, et al. Efficacy and effectiveness of COVID-19 vaccines against SARS-CoV-2 infection: interim results of a living systematic review, 1 January to 14 May 2021. Euro Surveill. 2021;26(28):2100563.  https://doi.org/10.2807/1560-7917.ES.2021.26.28.2100563  PMID: 34269175 
  5. Ministero della Salute. Piano strategico per la vaccinazione anti-SARS-CoV-2/COVID-19. [Strategic plan for SARS-CoV-2 / COVID-19 vaccination]. Rome: Ministero della Salute; 2020. Italian. Available from: https://www.trovanorme.salute.gov.it/norme/renderNormsanPdf?anno=2021&codLeg=78657&parte=1&serie=null
  6. Eurostat. NUTS, Nomenclature of territorial units for statistics. Luxembourg: Eurostat. [Accessed: 25 Oct 2021]. Available from: https://ec.europa.eu/eurostat/web/nuts/background
  7. Lopez Bernal J, Andrews N, Gower C, Robertson C, Stowe J, Tessier E, et al. Effectiveness of the Pfizer-BioNTech and Oxford-AstraZeneca vaccines on covid-19 related symptoms, hospital admissions, and mortality in older adults in England: test negative case-control study. BMJ. 2021;373(1088):n1088.  https://doi.org/10.1136/bmj.n1088  PMID: 33985964 
  8. Baden LR, El Sahly HM, Essink B, Kotloff K, Frey S, Novak R, et al. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine. N Engl J Med. 2021;384(5):403-16.  https://doi.org/10.1056/NEJMoa2035389  PMID: 33378609 
  9. Riccardo F, Ajelli M, Andrianou XD, Bella A, Del Manso M, Fabiani M, et al. Epidemiological characteristics of COVID-19 cases and estimates of the reproductive numbers 1 month into the epidemic, Italy, 28 January to 31 March 2020. Euro Surveill. 2020;25(49):2000790.  https://doi.org/10.2807/1560-7917.ES.2020.25.49.2000790  PMID: 33303064 
  10. Governo Italiano. Presidenza del Consiglio dei Ministri. Data Repository. [Accessed: 11 Nov 2021]. Italian. Available from: https://github.com/italia/covid19-opendata-vaccini
  11. Bonmarin I, Belchior E, Lévy-Bruhl D. Impact of influenza vaccination on mortality in the French elderly population during the 2000-2009 period. Vaccine. 2015;33(9):1099-101.  https://doi.org/10.1016/j.vaccine.2015.01.023  PMID: 25604800 
  12. Machado A, Mazagatos C, Dijkstra F, Kislaya I, Gherasim A, McDonald SA, et al. Impact of influenza vaccination programmes among the elderly population on primary care, Portugal, Spain and the Netherlands: 2015/16 to 2017/18 influenza seasons. Euro Surveill. 2019;24(45):1900268.  https://doi.org/10.2807/1560-7917.ES.2019.24.45.1900268  PMID: 31718740 
  13. Public Health England (PHE). Impact of COVID-19 vaccines on mortality in England - December 2020 to March 2021. London: PHE; 2021. Available from: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/972592/COVID-19_vaccine_impact_on_mortality_240321.pdf
  14. R Core Team. R: A language and environment for statistical computing. Vienna: R Foundation for Statistical Computing. [Accessed: 25 Oct 2021]. Available from: https://www.R-project.org/.
  15. Galvani A, Moghadas SM, Schneider EC. Deaths and hospitalizations averted by rapid US vaccination rollout. The Commonwealth Fund. Issue Briefs.2021; (July):7.
  16. Hyams C, Marlow R, Maseko Z, King J, Ward L, Fox K, et al. Effectiveness of BNT162b2 and ChAdOx1 nCoV-19 COVID-19 vaccination at preventing hospitalisations in people aged at least 80 years: a test-negative, case-control study. Lancet Infect Dis. 2021;21(11):1539-48.  https://doi.org/10.1016/S1473-3099(21)00330-3  PMID: 34174190 
  17. Goldstein JR, Cassidy T, Wachter KW. Vaccinating the oldest against COVID-19 saves both the most lives and most years of life. Proc Natl Acad Sci USA. 2021;118(11):e2026322118.  https://doi.org/10.1073/pnas.2026322118  PMID: 33632802 
  18. Victora PC, Castro PMC, Gurzenda S, Medeiros AC, França GVA, Barros PAJD. Estimating the early impact of vaccination against COVID-19 on deaths among elderly people in Brazil: Analyses of routinely-collected data on vaccine coverage and mortality. EClinicalMedicine. 2021;38:101036.  https://doi.org/10.1016/j.eclinm.2021.101036  PMID: 34308302 
  19. Lopez Bernal J, Andrews N, Gower C, Gallagher E, Simmons R, Thelwall S, et al. Effectiveness of Covid-19 vaccines against the B. 1.617. 2 (Delta) variant. N Engl J Med. 2021;385(7):585-94.  https://doi.org/10.1056/NEJMoa2108891  PMID: 34289274 
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