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Abstract

We report a large-scale outbreak of hand, foot and mouth disease (HFMD) in France. As at 28 September 2021, 3,403 cases have been reported (47% higher than in 2018–19). We prospectively analysed 210 clinical samples; 190 (90.5%) were enterovirus-positive. Most children presented with atypical HFMD. Coxsackievirus (CV)A6 (49.5%; 94/190) was predominant; no enterovirus A71 was detected. Dermatological and neurological complications of HFMD justify prospective syndromic and virological surveillance for early detection of HFMD outbreaks and identification of associated types.

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/content/10.2807/1560-7917.ES.2021.26.43.2100978
2021-10-28
2024-12-22
/content/10.2807/1560-7917.ES.2021.26.43.2100978
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A large-scale outbreak of hand, foot and mouth disease, France, as at 28 September 2021
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Audrey+Mirand&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mirand Audrey</a>, <a href="/search?value1=Robert+Cohen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cohen Robert</a>, <a href="/search?value1=Maxime+Bisseux&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bisseux Maxime</a>, <a href="/search?value1=St%C3%A9phanie+Tomba&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Tomba Stéphanie</a>, <a href="/search?value1=Fabienne+Cahn+Sellem&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sellem Fabienne Cahn</a>, <a href="/search?value1=Nathalie+Gelbert&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gelbert Nathalie</a>, <a href="/search?value1=St%C3%A9phane+B%C3%A9chet&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Béchet Stéphane</a>, <a href="/search?value1=Bruno+Frandji&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Frandji Bruno</a>, <a href="/search?value1=Christine+Archimbaud&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Archimbaud Christine</a>, <a href="/search?value1=Am%C3%A9lie+Brebion&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Brebion Amélie</a>, <a href="/search?value1=H%C3%A9l%C3%A8ne+Chabrolles&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Chabrolles Hélène</a>, <a href="/search?value1=Christel+Regagnon&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Regagnon Christel</a>, <a href="/search?value1=Corinne+Levy&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Levy Corinne</a>, <a href="/search?value1=Jean-Luc+Bailly&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bailly Jean-Luc</a>, <a href="/search?value1=C%C3%A9cile+Henquell&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Henquell Cécile</a></span>. A large-scale outbreak of hand, foot and mouth disease, France, as at 28 September 2021. <a href="/content/ecdc">Euro Surveill.</a> 2021;26(43):pii=2100978. <a href="https://doi.org/10.2807/1560-7917.ES.2021.26.43.2100978" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2021.26.43.2100978</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 14 Oct 2021;&nbsp;&nbsp; <span class="generated">Accepted</span>: 28 Oct 2021 </span> </p>
/content/10.2807/1560-7917.ES.2021.26.43.2100978
/content/10.2807/1560-7917.ES.2021.26.43.2100978
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