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Abstract

Through deterministic data linkage of health registries, mRNA vaccine effectiveness (VE) against COVID-19-related hospitalisations and deaths was measured in 1,880,351 older adults. VE against hospitalisations was 94% (95% confidence interval (CI): 88–97) and 82% (95% CI: 72–89) for those 65–79 and ≥ 80 years old, with no evidence of waning 98 days after dose two. VE against mortality was 96% (95% CI: 92–98) and 81% (95% CI: 74–87) in these two age groups.

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/content/10.2807/1560-7917.ES.2021.26.38.2100833
2021-09-23
2024-11-21
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2021.26.38.2100833
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mRNA vaccine effectiveness against COVID-19-related hospitalisations and deaths in older adults: a cohort study based on data linkage of national health registries in Portugal, February to August 2021
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Baltazar+Nunes&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nunes Baltazar</a>, <a href="/search?value1=Ana+Paula+Rodrigues&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rodrigues Ana Paula</a>, <a href="/search?value1=Irina+Kislaya&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kislaya Irina</a>, <a href="/search?value1=Camila+Cruz&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cruz Camila</a>, <a href="/search?value1=Andr%C3%A9+Peralta-Santos&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Peralta-Santos André</a>, <a href="/search?value1=Jo%C3%A3o+Lima&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lima João</a>, <a href="/search?value1=Pedro++Pinto+Leite&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pinto Leite Pedro </a>, <a href="/search?value1=Duarte+Sequeira&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sequeira Duarte</a>, <a href="/search?value1=Carlos++Matias+Dias&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Matias Dias Carlos </a>, <a href="/search?value1=Ausenda+Machado&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Machado Ausenda</a></span>. mRNA vaccine effectiveness against COVID-19-related hospitalisations and deaths in older adults: a cohort study based on data linkage of national health registries in Portugal, February to August 2021. <a href="/content/ecdc">Euro Surveill.</a> 2021;26(38):pii=2100833. <a href="https://doi.org/10.2807/1560-7917.ES.2021.26.38.2100833" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2021.26.38.2100833</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 27 Aug 2021;&nbsp;&nbsp; <span class="generated">Accepted</span>: 22 Sept 2021 </span> </p>
/content/10.2807/1560-7917.ES.2021.26.38.2100833
/content/10.2807/1560-7917.ES.2021.26.38.2100833
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