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Abstract

We compared PCR results from SARS-CoV-2-positive patients tested in the community in France from 14 June to 30 July 2021. In asymptomatic individuals, Cq values were significantly higher in fully vaccinated than non-fully vaccinated individuals (effect size: 1.7; 95% CI: 1–2.3; p < 10−6). In symptomatic individuals and controlling for time since symptoms, the difference vanished (p = 0.26). Infections with the Delta variant had lower Cq values at symptom onset than with Alpha (effect size: −3.32; 95% CI: −4.38 to −2.25; p < 10−6).

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2021-09-16
2024-12-22
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Characterisation of vaccine breakthrough infections of SARS-CoV-2 Delta and Alpha variants and within-host viral load dynamics in the community, France, June to July 2021
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Fran%C3%A7ois+Blanquart&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Blanquart François</a>, <a href="/search?value1=Cl%C3%A9mence+Abad&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Abad Clémence</a>, <a href="/search?value1=Jo%C3%ABvin+Ambroise&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ambroise Joëvin</a>, <a href="/search?value1=Mathieu+Bernard&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bernard Mathieu</a>, <a href="/search?value1=Gina+Cosentino&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cosentino Gina</a>, <a href="/search?value1=Jean-Marc+Giannoli&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Giannoli Jean-Marc</a>, <a href="/search?value1=Florence+D%C3%A9barre&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Débarre Florence</a></span>. Characterisation of vaccine breakthrough infections of SARS-CoV-2 Delta and Alpha variants and within-host viral load dynamics in the community, France, June to July 2021. <a href="/content/ecdc">Euro Surveill.</a> 2021;26(37):pii=2100824. <a href="https://doi.org/10.2807/1560-7917.ES.2021.26.37.2100824" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2021.26.37.2100824</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 25 Aug 2021 </span> </p>
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