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Abstract

Several studies report high effectiveness of COVID-19 vaccines against SARS-CoV-2 infection and severe disease, however an important knowledge gap is the vaccine effectiveness against transmission (VET). We present estimates of the VET to household and other close contacts in the Netherlands, from February to May 2021, using contact monitoring data. The secondary attack rate among household contacts was lower for fully vaccinated than unvaccinated index cases (11% vs 31%), with an adjusted VET of 71% (95% confidence interval: 63–77).

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/content/10.2807/1560-7917.ES.2021.26.31.2100640
2021-08-05
2024-11-21
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2021.26.31.2100640
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Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Brechje+de+Gier&option1=author&noRedirect=true" class="nonDisambigAuthorLink">de Gier Brechje</a>, <a href="/search?value1=Stijn+Andeweg&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Andeweg Stijn</a>, <a href="/search?value1=Rosa+Joosten&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Joosten Rosa</a>, <a href="/search?value1=Ronald+ter+Schegget&option1=author&noRedirect=true" class="nonDisambigAuthorLink">ter Schegget Ronald</a>, <a href="/search?value1=Naomi+Smorenburg&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Smorenburg Naomi</a>, <a href="/search?value1=Jan+van+de+Kassteele&option1=author&noRedirect=true" class="nonDisambigAuthorLink">van de Kassteele Jan</a>, <a href="/search?value1=RIVM+COVID-19+surveillance+and+epidemiology+team+1%2C&option1=author&noRedirect=true" class="nonDisambigAuthorLink">RIVM COVID-19 surveillance and epidemiology team 1,</a>, <a href="/search?value1=Susan+JM+Hahn%C3%A9&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hahné Susan JM</a>, <a href="/search?value1=Susan+van+den+Hof&option1=author&noRedirect=true" class="nonDisambigAuthorLink">van den Hof Susan</a>, <a href="/search?value1=Hester+E+de+Melker&option1=author&noRedirect=true" class="nonDisambigAuthorLink">de Melker Hester E</a>, <a href="/search?value1=Mirjam+J+Knol&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Knol Mirjam J</a></span>. Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021. <a href="/content/ecdc">Euro Surveill.</a> 2021;26(31):pii=2100640. <a href="https://doi.org/10.2807/1560-7917.ES.2021.26.31.2100640" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2021.26.31.2100640</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 29 Jun 2021;&nbsp;&nbsp; <span class="generated">Accepted</span>: 02 Aug 2021 </span> </p>
/content/10.2807/1560-7917.ES.2021.26.31.2100640
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