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Abstract

SARS-CoV-2 variants of concern (VOC) should not escape molecular surveillance. We investigated if SARS-CoV-2 rapid antigen tests (RATs) could detect B.1.1.7 and B.1.351 VOCs in certain laboratory conditions. Infectious cell culture supernatants containing B.1.1.7, B.1.351 or non-VOC SARS-CoV-2 were respectively diluted both in DMEM and saliva. Dilutions were analysed with Roche, Siemens, Abbott, nal von minden and RapiGEN RATs. While further studies with appropriate real-life clinical samples are warranted, all RATs detected B.1.1.7 and B.1.351, generally comparable to non-VOC strain.

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Addendum
An addendum has been published for this content:
Addendum for Euro Surveill. 2021;26(16)
Addendum
An addendum has been published for this content:
Addendum for Euro Surveill. 2021;26(16)
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/content/10.2807/1560-7917.ES.2021.26.16.2100413
2021-04-22
2024-11-09
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2021.26.16.2100413
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Detection of the new SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in five SARS-CoV-2 rapid antigen tests (RATs), Germany, March 2021
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Sabrina+Jungnick&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Jungnick Sabrina</a>, <a href="/search?value1=Bernhard+Hobmaier&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hobmaier Bernhard</a>, <a href="/search?value1=Lena+Mautner&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mautner Lena</a>, <a href="/search?value1=Mona+Hoyos&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hoyos Mona</a>, <a href="/search?value1=Maren+Haase&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Haase Maren</a>, <a href="/search?value1=Armin+Baiker&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Baiker Armin</a>, <a href="/search?value1=Heidi+Lahne&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lahne Heidi</a>, <a href="/search?value1=Ute+Eberle&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Eberle Ute</a>, <a href="/search?value1=Clara+Wimmer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wimmer Clara</a>, <a href="/search?value1=Sabrina+Hepner&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hepner Sabrina</a>, <a href="/search?value1=Annika+Sprenger&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sprenger Annika</a>, <a href="/search?value1=Carola+Berger&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Berger Carola</a>, <a href="/search?value1=Alexandra+Dangel&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Dangel Alexandra</a>, <a href="/search?value1=Manfred+Wildner&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wildner Manfred</a>, <a href="/search?value1=Bernhard+Liebl&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Liebl Bernhard</a>, <a href="/search?value1=Nikolaus+Ackermann&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ackermann Nikolaus</a>, <a href="/search?value1=Andreas+Sing&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sing Andreas</a>, <a href="/search?value1=Volker+Fingerle&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fingerle Volker</a>, <a href="/search?value1=the+Bavarian+SARS-CoV-2-Public+Health+Laboratory+Team&option1=author&noRedirect=true" class="nonDisambigAuthorLink">the Bavarian SARS-CoV-2-Public Health Laboratory Team</a></span>. Detection of the new SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in five SARS-CoV-2 rapid antigen tests (RATs), Germany, March 2021. <a href="/content/ecdc">Euro Surveill.</a> 2021;26(16):pii=2100413. <a href="https://doi.org/10.2807/1560-7917.ES.2021.26.16.2100413" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2021.26.16.2100413</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 12 Apr 2021;&nbsp;&nbsp; <span class="generated">Accepted</span>: 22 Apr 2021 </span> </p>
/content/10.2807/1560-7917.ES.2021.26.16.2100413
/content/10.2807/1560-7917.ES.2021.26.16.2100413
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