Detection of SARS-CoV-2 lineage P.1 in patients from a region with exponentially increasing hospitalisation rate, February 2021, Rio Grande do Sul, Southern Brazil

Andreza Francisco Martins; Alexandre Prehn Zavascki; Priscila Lamb Wink; Fabiana Caroline Zempulski Volpato; Francielle Liz Monteiro; Clévia Rosset; Fernanda De-Paris; Álvaro Krüger Ramos; Afonso Luís Barth

doi:10.2807/1560-7917.ES.2021.26.12.2100276

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Detection of SARS-CoV-2 lineage P.1 in patients from a region with exponentially increasing hospitalisation rate, February 2021, Rio Grande do Sul, Southern Brazil
Andreza Francisco Martins^1,2,3,4 , Alexandre Prehn Zavascki^1,4,5,6 , Priscila Lamb Wink^1,2,7 , Fabiana Caroline Zempulski Volpato^1,7,8 , Francielle Liz Monteiro^1,7 , Clévia Rosset^7,9 , Fernanda De-Paris^1,7 , Álvaro Krüger Ramos¹⁰ , Afonso Luís Barth^1,2,7,8
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Affiliations: ¹ LABRESIS – Laboratório de Pesquisa em Resistência Bacteriana, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil ² Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil ³ Bioinformatic Core, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil ⁴ These authors contributed equally to the work as first authors. ⁵ Internal Medicine Department, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil ⁶ Infectious Diseases Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil ⁷ Laboratório de Diagnóstico de SARS-CoV-2, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil ⁸ Programa de Pós-Graduação em Ciências Médicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil ⁹ Laboratório de Medicina Genômica (LMG), Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil ¹⁰ Programa de Pós-Graduação em Matemática, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

Correspondence:
Priscila Lamb Wink
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Citation style for this article: Martins Andreza Francisco, Zavascki Alexandre Prehn, Wink Priscila Lamb, Volpato Fabiana Caroline Zempulski, Monteiro Francielle Liz, Rosset Clévia, De-Paris Fernanda, Ramos Álvaro Krüger, Barth Afonso Luís. Detection of SARS-CoV-2 lineage P.1 in patients from a region with exponentially increasing hospitalisation rate, February 2021, Rio Grande do Sul, Southern Brazil. Euro Surveill. 2021;26(12):pii=2100276. https://doi.org/10.2807/1560-7917.ES.2021.26.12.2100276 Received: 09 Mar 2021; Accepted: 25 Mar 2021

Abstract

The emergence of SARS-CoV-2 P.1 lineage coincided with a surge in hospitalisations in the North region of Brazil. In the South region’s Rio Grande do Sul state, severe COVID-19 case numbers rose 3.8 fold in February 2021. During that month, at a COVID-19 referral hospital in this state, whole-genome sequencing of a subset of cases’ specimens (n = 27) revealed P.1 lineage SARS-CoV-2 in most (n = 24). Findings raise concerns regarding a possible association between lineage P.1 and rapid case and hospitalisation increases.

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2021-03-25

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Detection of SARS-CoV-2 lineage P.1 in patients from a region with exponentially increasing hospitalisation rate, February 2021, Rio Grande do Sul, Southern Brazil

Citation style for this article: <a href="/search?value1=Andreza+Francisco+Martins&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Martins Andreza Francisco</a>, <a href="/search?value1=Alexandre+Prehn+Zavascki&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zavascki Alexandre Prehn</a>, <a href="/search?value1=Priscila+Lamb+Wink&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wink Priscila Lamb</a>, <a href="/search?value1=Fabiana+Caroline+Zempulski+Volpato&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Volpato Fabiana Caroline Zempulski</a>, <a href="/search?value1=Francielle+Liz+Monteiro&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Monteiro Francielle Liz</a>, <a href="/search?value1=Cl%C3%A9via+Rosset&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rosset Clévia</a>, <a href="/search?value1=Fernanda+De-Paris&option1=author&noRedirect=true" class="nonDisambigAuthorLink">De-Paris Fernanda</a>, <a href="/search?value1=%C3%81lvaro+Kr%C3%BCger+Ramos&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ramos Álvaro Krüger</a>, <a href="/search?value1=Afonso+Lu%C3%ADs+Barth&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Barth Afonso Luís</a>. Detection of SARS-CoV-2 lineage P.1 in patients from a region with exponentially increasing hospitalisation rate, February 2021, Rio Grande do Sul, Southern Brazil. <a href="/content/ecdc">Euro Surveill.</a> 2021;26(12):pii=2100276. <a href="https://doi.org/10.2807/1560-7917.ES.2021.26.12.2100276" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2021.26.12.2100276</a> Received: 09 Mar 2021;   Accepted: 25 Mar 2021

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Detection of SARS-CoV-2 lineage P.1 in patients from a region with exponentially increasing hospitalisation rate, February 2021, Rio Grande do Sul, Southern Brazil

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