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Abstract

We show that the SARS-CoV-2 B.1.1.7 lineage is highly disseminated in Portugal, with the odds of B.1.1.7 proportion increasing at an estimated 89% (95% confidence interval: 83–95%) per week until week 3 2021. RT-PCR spike gene target late detection (SGTL) can constitute a useful surrogate to track B.1.1.7 spread, besides the spike gene target failure (SGTF) proxy. SGTL/SGTF samples were associated with statistically significant higher viral loads, but not with substantial shift in age distribution compared to non-SGTF/SGTL cases.

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/content/10.2807/1560-7917.ES.2021.26.10.2100130
2021-03-11
2024-12-03
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2021.26.10.2100130
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Tracking SARS-CoV-2 lineage B.1.1.7 dissemination: insights from nationwide spike gene target failure (SGTF) and spike gene late detection (SGTL) data, Portugal, week 49 2020 to week 3 2021
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=V%C3%ADtor+Borges&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Borges Vítor</a>, <a href="/search?value1=Carlos+Sousa&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sousa Carlos</a>, <a href="/search?value1=Lu%C3%ADs+Menezes&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Menezes Luís</a>, <a href="/search?value1=Ant%C3%B3nio+Maia+Gon%C3%A7alves&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gonçalves António Maia</a>, <a href="/search?value1=Miguel+Pic%C3%A3o&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Picão Miguel</a>, <a href="/search?value1=Jos%C3%A9+Pedro+Almeida&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Almeida José Pedro</a>, <a href="/search?value1=Margarida+Vieita&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Vieita Margarida</a>, <a href="/search?value1=Rafael+Santos&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Santos Rafael</a>, <a href="/search?value1=Ana+Rita+Silva&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Silva Ana Rita</a>, <a href="/search?value1=Mariana+Costa&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Costa Mariana</a>, <a href="/search?value1=Lu%C3%ADs+Carneiro&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Carneiro Luís</a>, <a href="/search?value1=Pedro+Casaca&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Casaca Pedro</a>, <a href="/search?value1=Pedro+Pinto-Leite&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pinto-Leite Pedro</a>, <a href="/search?value1=Andr%C3%A9+Peralta-Santos&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Peralta-Santos André</a>, <a href="/search?value1=Joana+Isidro&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Isidro Joana</a>, <a href="/search?value1=S%C3%ADlvia+Duarte&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Duarte Sílvia</a>, <a href="/search?value1=Lu%C3%ADs+Vieira&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Vieira Luís</a>, <a href="/search?value1=Raquel+Guiomar&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Guiomar Raquel</a>, <a href="/search?value1=Susana+Silva&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Silva Susana</a>, <a href="/search?value1=Baltazar+Nunes&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nunes Baltazar</a>, <a href="/search?value1=Jo%C3%A3o+P+Gomes&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gomes João P</a></span>. Tracking SARS-CoV-2 lineage B.1.1.7 dissemination: insights from nationwide spike gene target failure (SGTF) and spike gene late detection (SGTL) data, Portugal, week 49 2020 to week 3 2021. <a href="/content/ecdc">Euro Surveill.</a> 2021;26(10):pii=2100131. <a href="https://doi.org/10.2807/1560-7917.ES.2021.26.10.2100130" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2021.26.10.2100130</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 05 Feb 2021;&nbsp;&nbsp; <span class="generated">Accepted</span>: 11 Mar 2021 </span> </p>
/content/10.2807/1560-7917.ES.2021.26.10.2100130
/content/10.2807/1560-7917.ES.2021.26.10.2100130
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