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Abstract

A large outbreak of New Delhi metallo-beta-lactamase (NDM)-1-producing sequence type (ST) 147 occurred in Tuscany, Italy in 2018–2019. In 2020, ST147 NDM-9-producing were detected at the University Hospital of Pisa, Tuscany, in two critically ill patients; one developed bacteraemia. Genomic and phylogenetic analyses suggest relatedness of 2018–2019 and 2020 strains, with a change from NDM-1 to NDM-9 in the latter and evolution by colistin, tigecycline and fosfomycin resistance acquisition.

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/content/10.2807/1560-7917.ES.2020.25.48.2001779
2020-12-03
2025-02-21
/content/10.2807/1560-7917.ES.2020.25.48.2001779
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Extremely drug-resistant NDM-9-producing ST147 Klebsiella pneumoniae causing infections in Italy, May 2020
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Marco+Falcone&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Falcone Marco</a>, <a href="/search?value1=Cesira+Giordano&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Giordano Cesira</a>, <a href="/search?value1=Simona+Barnini&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Barnini Simona</a>, <a href="/search?value1=Giusy+Tiseo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Tiseo Giusy</a>, <a href="/search?value1=Alessandro+Leonildi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Leonildi Alessandro</a>, <a href="/search?value1=Paolo+Malacarne&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Malacarne Paolo</a>, <a href="/search?value1=Francesco+Menichetti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Menichetti Francesco</a>, <a href="/search?value1=Alessandra+Carattoli&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Carattoli Alessandra</a></span>. Extremely drug-resistant NDM-9-producing ST147 Klebsiella pneumoniae causing infections in Italy, May 2020. <a href="/content/ecdc">Euro Surveill.</a> 2020;25(48):pii=2001779. <a href="https://doi.org/10.2807/1560-7917.ES.2020.25.48.2001779" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2020.25.48.2001779</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 09 Oct 2020;&nbsp;&nbsp; <span class="generated">Accepted</span>: 03 Dec 2020 </span> </p>
/content/10.2807/1560-7917.ES.2020.25.48.2001779
/content/10.2807/1560-7917.ES.2020.25.48.2001779
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