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Emergence of carbapenem-resistant ST131 Escherichia coli carrying blaOXA-244 in Germany, 2019 to 2020
- Sybille Welker1 , Sébastien Boutin2 , Thomas Miethke1 , Klaus Heeg2 , Dennis Nurjadi2
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View Affiliations Hide AffiliationsAffiliations: 1 Institute for Medical Microbiology and Hygiene, Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany 2 Medical Microbiology and Hygiene, Department of Infectious Diseases, Heidelberg University Hospital, Heidelberg, GermanyDennis Nurjadidennis.nurjadi uni-heidelberg.de
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Citation style for this article: Welker Sybille, Boutin Sébastien, Miethke Thomas, Heeg Klaus, Nurjadi Dennis. Emergence of carbapenem-resistant ST131 Escherichia coli carrying blaOXA-244 in Germany, 2019 to 2020. Euro Surveill. 2020;25(46):pii=2001815. https://doi.org/10.2807/1560-7917.ES.2020.25.46.2001815 Received: 19 Oct 2020; Accepted: 18 Nov 2020
Abstract
The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing E. coli may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 E. coli is of clinical relevance and should be monitored closely.
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