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Abstract

We analysed 5,484 close contacts of coronavirus disease (COVID-19) cases in Italy, all tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Infection fatality ratio was 0.43% (95% confidence interval (CI): 0.21–0.79) for individuals younger than 70 years and 10.5% (95% CI: 8.0–13.6) for older individuals. Risk of death after infection was 62% lower (95% CI: 31–80) in clusters identified after 16 March 2020 and 1.8-fold higher for males (95% CI: 1.03–3.16).

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/content/10.2807/1560-7917.ES.2020.25.31.2001383
2020-08-06
2024-11-21
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2020.25.31.2001383
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Age-specific SARS-CoV-2 infection fatality ratio and associated risk factors, Italy, February to April 2020
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Piero+Poletti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Poletti Piero</a>, <a href="/search?value1=Marcello+Tirani&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Tirani Marcello</a>, <a href="/search?value1=Danilo+Cereda&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cereda Danilo</a>, <a href="/search?value1=Filippo+Trentini&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Trentini Filippo</a>, <a href="/search?value1=Giorgio+Guzzetta&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Guzzetta Giorgio</a>, <a href="/search?value1=Valentina+Marziano&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Marziano Valentina</a>, <a href="/search?value1=Sabrina+Buoro&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Buoro Sabrina</a>, <a href="/search?value1=Simona+Riboli&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Riboli Simona</a>, <a href="/search?value1=Lucia+Crottogini&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Crottogini Lucia</a>, <a href="/search?value1=Raffaella+Piccarreta&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Piccarreta Raffaella</a>, <a href="/search?value1=Alessandra+Piatti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Piatti Alessandra</a>, <a href="/search?value1=Giacomo+Grasselli&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Grasselli Giacomo</a>, <a href="/search?value1=Alessia+Melegaro&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Melegaro Alessia</a>, <a href="/search?value1=Maria+Gramegna&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gramegna Maria</a>, <a href="/search?value1=Marco+Ajelli&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ajelli Marco</a>, <a href="/search?value1=Stefano+Merler&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Merler Stefano</a></span>. Age-specific SARS-CoV-2 infection fatality ratio and associated risk factors, Italy, February to April 2020. <a href="/content/ecdc">Euro Surveill.</a> 2020;25(31):pii=2001383. <a href="https://doi.org/10.2807/1560-7917.ES.2020.25.31.2001383" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2020.25.31.2001383</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 14 Jul 2020;&nbsp;&nbsp; <span class="generated">Accepted</span>: 04 Aug 2020 </span> </p>
/content/10.2807/1560-7917.ES.2020.25.31.2001383
/content/10.2807/1560-7917.ES.2020.25.31.2001383
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