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Abstract

Analysis of sequencing data for 143 - and -positive isolates from 13 European national collections and the public domain resulted in the identification of 15 previously undetected multi-country transmission clusters. For 10 clusters, cases had prior travel/hospitalisation history in countries outside of the European Union including Egypt, Iran, Morocco, Russia, Serbia, Tunisia and Turkey. These findings highlight the benefit of European whole genome sequencing-based surveillance and data sharing for control of antimicrobial resistance.

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/content/10.2807/1560-7917.ES.2020.25.20.2000627
2020-05-21
2024-11-24
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2020.25.20.2000627
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References

  1. European Centre for Disease Prevention and Control (ECDC). Rapid risk assessment: Outbreak of carbapenemase-producing (NDM-1 and OXA-48) and colistin-resistant Klebsiella pneumoniae ST307, north-east Germany, 2019. Stockholm: ECDC; 2019. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/Klebsiella-pneumoniae-resistance-Germany-risk-assessment.pdf
  2. Haller S, Kramer R, Becker K, Bohnert JA, Eckmanns T, Hans JB, et al. Extensively drug-resistant Klebsiella pneumoniae ST307 outbreak, north-eastern Germany, June to October 2019. Euro Surveill. 2019;24(50):1900734.  https://doi.org/10.2807/1560-7917.ES.2019.24.50.1900734  PMID: 31847948 
  3. Kumar N, Raven KE, Blane B, Leek D, Brown NM, Bragin E, et al. Evaluation of a fully automated bioinformatics tool to predict antibiotic resistance from MRSA genomes. J Antimicrob Chemother. 2020;75(5):1117-22.  https://doi.org/10.1093/jac/dkz570  PMID: 32025709 
  4. Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees. Heidelberg: EMBL. [Accessed: 7 May 2020]. Available from: https://itol.embl.de/
  5. Zankari E, Hasman H, Cosentino S, Vestergaard M, Rasmussen S, Lund O, et al. Identification of acquired antimicrobial resistance genes. J Antimicrob Chemother. 2012;67(11):2640-4.  https://doi.org/10.1093/jac/dks261  PMID: 22782487 
  6. Kleborate v0·3·0. San Francisco: GitHub. [Accessed: 16 Dec 2019]. Available from: https://github.com/katholt/Kleborate
  7. European Nucleotide Archive. Study: PRJEB35890. European study on Klebsiella pneumoniae carrying both NDM-1 and OXA-48. Hinxton: The European Bioinformatics Institute (EMBL-EBI); 2020. Available from: www.ebi.ac.uk/ena/data/view/PRJEB35890
  8. European Centre for Disease Prevention and Control (ECDC). Rapid risk assessment: Regional outbreak of New Delhi metallo-betalactamase-producing carbapenem-resistant Enterobacteriaceae, Italy, 2018-2019. Stockholm ECDC; 2019. Available from: https://ecdc.europa.eu/sites/portal/files/documents/04-Jun-2019-RRA-Carbapenems%2C%20Enterobacteriaceae-Italy.pdf
  9. European Centre for Disease Prevention and Control (ECDC). Rapid risk assessment: Outbreak of carbapenemase-producing Enterobacterales in Lithuania, 2019. Stockholm: ECDC; 2019. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/AMR-rapid-risk-assessment-outbreak%20-of-carbapenemase-producing-Enterobacterales-Lithuania.pdf
  10. Shamina OV, Kryzhanovskaya OA, Lazareva AV, Alyabieva NM, Polikarpova SV, Karaseva OV, et al. Emergence of the ST307 clone carrying a novel insertion element MITEKpn1 in the mgrB gene among carbapenem-resistant Klebsiella pneumoniae from Moscow, Russia. Int J Antimicrob Agents. 2020;55(2):105850.  https://doi.org/10.1016/j.ijantimicag.2019.11.007  PMID: 31770629 
  11. Barguigua A, El Otmani F, Lakbakbi El Yaagoubi F, Talmi M, Zerouali K, Timinouni M. First report of a Klebsiella pneumoniae strain coproducing NDM-1, VIM-1 and OXA-48 carbapenemases isolated in Morocco. APMIS. 2013;121(7):675-7.  https://doi.org/10.1111/apm.12034  PMID: 23278254 
  12. Ben Nasr A, Decré D, Compain F, Genel N, Barguellil F, Arlet G. Emergence of NDM-1 in association with OXA-48 in Klebsiella pneumoniae from Tunisia. Antimicrob Agents Chemother. 2013;57(8):4089-90.  https://doi.org/10.1128/AAC.00536-13  PMID: 23752514 
  13. Solgi H, Giske CG, Badmasti F, Aghamohammad S, Havaei SA, Sabeti S, et al. Emergence of carbapenem resistant Escherichia coli isolates producing blaNDM and blaOXA-48-like carried on IncA/C and IncL/M plasmids at two Iranian university hospitals. Infect Genet Evol. 2017;55:318-23.  https://doi.org/10.1016/j.meegid.2017.10.003  PMID: 28987805 
  14. Khalifa HO, Soliman AM, Ahmed AM, Shimamoto T, Hara T, Ikeda M, et al. High carbapenem resistance in clinical gram-negative pathogens isolated in Egypt. Microb Drug Resist. 2017;23(7):838-44.  https://doi.org/10.1089/mdr.2015.0339  PMID: 28191865 
  15. Cizmeci Z, Aktas E, Otlu B, Acikgoz O, Ordekci S. Molecular characterization of carbapenem- resistant Enterobacteriaceae yields increasing rates of NDM-1 carbapenemases and colistin resistance in an OXA-48- endemic area. J Chemother. 2017;29(6):344-50.  https://doi.org/10.1080/1120009X.2017.1323149  PMID: 28486840 
  16. Revez J, Espinosa L, Albiger B, Leitmeyer KC, Struelens MJECDC National Microbiology Focal Points and Experts Group. Survey on the use of whole-genome sequencing for infectious diseases surveillance: rapid expansion of European national capacities, 2015-2016. Front Public Health. 2017;5:347.  https://doi.org/10.3389/fpubh.2017.00347  PMID: 29326921 
  17. European Centre for Disease Prevention and Control (ECDC). Monitoring the use of whole-genome sequencing in infectious disease surveillance in Europe 2015–2017. Stockholm: ECDC; 2018. Available from: https://www.ecdc.europa.eu/sites/portal/files/documents/whole-genome-sequencing-infectious-disease-surveillance-Europe-2015-2017.pdf
Cross-border spread of blaNDM-1- and blaOXA-48-positive Klebsiella pneumoniae: a European collaborative analysis of whole genome sequencing and epidemiological data, 2014 to 2019
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Catherine+Ludden&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ludden Catherine</a>, <a href="/search?value1=Felix+L%C3%B6tsch&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lötsch Felix</a>, <a href="/search?value1=Erik+Alm&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Alm Erik</a>, <a href="/search?value1=Narender+Kumar&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kumar Narender</a>, <a href="/search?value1=Karin+Johansson&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Johansson Karin</a>, <a href="/search?value1=Barbara+Albiger&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Albiger Barbara</a>, <a href="/search?value1=Te-Din+Huang&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Huang Te-Din</a>, <a href="/search?value1=Olivier+Denis&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Denis Olivier</a>, <a href="/search?value1=Anette+M+Hammerum&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hammerum Anette M</a>, <a href="/search?value1=Henrik+Hasman&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hasman Henrik</a>, <a href="/search?value1=Jari+Jalava&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Jalava Jari</a>, <a href="/search?value1=Kati+R%C3%A4is%C3%A4nen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Räisänen Kati</a>, <a href="/search?value1=Laurent+Dortet&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Dortet Laurent</a>, <a href="/search?value1=Agn%C3%A8s+B+Jousset&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Jousset Agnès B</a>, <a href="/search?value1=S%C3%B6ren+Gatermann&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gatermann Sören</a>, <a href="/search?value1=Sebastian+Haller&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Haller Sebastian</a>, <a href="/search?value1=Martin+Cormican&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cormican Martin</a>, <a href="/search?value1=Wendy+Brennan&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Brennan Wendy</a>, <a href="/search?value1=Maria+Del+Grosso&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Del Grosso Maria</a>, <a href="/search?value1=Monica+Monaco&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Monaco Monica</a>, <a href="/search?value1=Leo+Schouls&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Schouls Leo</a>, <a href="/search?value1=%C3%98rjan+Samuelsen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Samuelsen Ørjan</a>, <a href="/search?value1=Mateja+Pir%C5%A1&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pirš Mateja</a>, <a href="/search?value1=Tja%C5%A1a+Cerar&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cerar Tjaša</a>, <a href="/search?value1=J%C3%A9sus+Oteo-Iglesias&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Oteo-Iglesias Jésus</a>, <a href="/search?value1=Maria+P%C3%A9rez-V%C3%A1zquez&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pérez-Vázquez Maria</a>, <a href="/search?value1=Karin+Sj%C3%B6str%C3%B6m&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sjöström Karin</a>, <a href="/search?value1=Petra+Edquist&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Edquist Petra</a>, <a href="/search?value1=Katie+L+Hopkins&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hopkins Katie L</a>, <a href="/search?value1=Marc+J+Struelens&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Struelens Marc J</a>, <a href="/search?value1=Daniel+Palm&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Palm Daniel</a>, <a href="/search?value1=Dominique+L+Monnet&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Monnet Dominique L</a>, <a href="/search?value1=Anke+Kohlenberg&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kohlenberg Anke</a></span>. Cross-border spread of blaNDM-1- and blaOXA-48-positive Klebsiella pneumoniae: a European collaborative analysis of whole genome sequencing and epidemiological data, 2014 to 2019. <a href="/content/ecdc">Euro Surveill.</a> 2020;25(20):pii=2000627. <a href="https://doi.org/10.2807/1560-7917.ES.2020.25.20.2000627" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2020.25.20.2000627</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 15 Apr 2020;&nbsp;&nbsp; <span class="generated">Accepted</span>: 19 May 2020 </span> </p>
/content/10.2807/1560-7917.ES.2020.25.20.2000627
/content/10.2807/1560-7917.ES.2020.25.20.2000627
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