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Clinical characteristics of coronavirus disease (COVID-19) early findings from a teaching hospital in Pavia, North Italy, 21 to 28 February 2020
- Marta Colaneri1 , Paolo Sacchi1 , Valentina Zuccaro1 , Simona Biscarini1 , Michele Sachs1 , Silvia Roda1 , Teresa Chiara Pieri1 , Pietro Valsecchi1 , Antonio Piralla2 , Elena Seminari1 , Angela Di Matteo1 , Stefano Novati1 , Laura Maiocchi1 , Layla Pagnucco1 , Marcello Tirani2,3 , Fausto Baldanti4,5 , Francesco Mojoli5,6,7 , Stefano Perlini8,9 , Raffaele Bruno1,5 , the COVID19 IRCCS San Matteo Pavia Task Force10
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View Affiliations Hide AffiliationsAffiliations: 1 Division of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy 2 Department of Hygiene and Preventive Medicine, Health Protection Agency of Pavia, Pavia, Italy 3 Directorate General for Health, Lombardy Region, Milano, Italy 4 Molecular Virology Unit, Microbiology and Virology Department, Pavia, Italy 5 Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy 6 Anesthesia and Intensive Care, Emergency Department, Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy 7 Anesthesia, Intensive Care and Pain Therapy, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy 8 Emergency Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy 9 Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy 10 The members of the COVID19 IRCCS San Matteo Pavia Task Force are listed at the end of the articleRaffaele Brunoraffaele.bruno unipv.it
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Citation style for this article: Colaneri Marta, Sacchi Paolo, Zuccaro Valentina, Biscarini Simona, Sachs Michele, Roda Silvia, Pieri Teresa Chiara, Valsecchi Pietro, Piralla Antonio, Seminari Elena, Di Matteo Angela, Novati Stefano, Maiocchi Laura, Pagnucco Layla, Tirani Marcello, Baldanti Fausto, Mojoli Francesco, Perlini Stefano, Bruno Raffaele, the COVID19 IRCCS San Matteo Pavia Task Force. Clinical characteristics of coronavirus disease (COVID-19) early findings from a teaching hospital in Pavia, North Italy, 21 to 28 February 2020. Euro Surveill. 2020;25(16):pii=2000460. https://doi.org/10.2807/1560-7917.ES.2020.25.16.2000460 Received: 29 Mar 2020; Accepted: 23 Apr 2020
Abstract
We describe clinical characteristics, treatments and outcomes of 44 Caucasian patients with coronavirus disease (COVID-19) at a single hospital in Pavia, Italy, from 21–28 February 2020, at the beginning of the outbreak in Europe. Seventeen patients developed severe disease, two died. After a median of 6 days, 14 patients were discharged from hospital. Predictors of lower odds of discharge were age > 65 years, antiviral treatment and for severe disease, lactate dehydrogenase > 300 mg/dL.
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