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Abstract

Whole genome sequences of SARS-CoV-2 obtained from two patients, a Chinese tourist visiting Rome and an Italian, were compared with sequences from Europe and elsewhere. In a phylogenetic tree, the Italian patient’s sequence clustered with sequences from Germany while the tourist’s sequence clustered with other European sequences. Some additional European sequences in the tree segregated outside the two clusters containing the patients’ sequences. This suggests multiple SARS-CoV-2 introductions in Europe or virus evolution during circulation.

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/content/10.2807/1560-7917.ES.2020.25.13.2000305
2020-04-02
2024-11-06
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2020.25.13.2000305
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Whole genome and phylogenetic analysis of two SARS-CoV-2 strains isolated in Italy in January and February 2020: additional clues on multiple introductions and further circulation in Europe
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Paola+Stefanelli&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Stefanelli Paola</a>, <a href="/search?value1=Giovanni+Faggioni&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Faggioni Giovanni</a>, <a href="/search?value1=Alessandra+Lo+Presti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lo Presti Alessandra</a>, <a href="/search?value1=Stefano+Fiore&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fiore Stefano</a>, <a href="/search?value1=Antonella+Marchi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Marchi Antonella</a>, <a href="/search?value1=Eleonora+Benedetti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Benedetti Eleonora</a>, <a href="/search?value1=Concetta+Fabiani&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fabiani Concetta</a>, <a href="/search?value1=Anna+Anselmo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Anselmo Anna</a>, <a href="/search?value1=Andrea+Ciammaruconi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ciammaruconi Andrea</a>, <a href="/search?value1=Antonella+Fortunato&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fortunato Antonella</a>, <a href="/search?value1=Riccardo+De+Santis&option1=author&noRedirect=true" class="nonDisambigAuthorLink">De Santis Riccardo</a>, <a href="/search?value1=Silvia+Fillo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fillo Silvia</a>, <a href="/search?value1=Maria+Rosaria+Capobianchi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Capobianchi Maria Rosaria</a>, <a href="/search?value1=Maria+Rita+Gismondo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gismondo Maria Rita</a>, <a href="/search?value1=Alessandra+Ciervo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ciervo Alessandra</a>, <a href="/search?value1=Giovanni+Rezza&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rezza Giovanni</a>, <a href="/search?value1=Maria+Rita+Castrucci&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Castrucci Maria Rita</a>, <a href="/search?value1=Florigio+Lista&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lista Florigio</a>, <a href="/search?value1=on+behalf+of+ISS+COVID-19+study+group&option1=author&noRedirect=true" class="nonDisambigAuthorLink">on behalf of ISS COVID-19 study group</a></span>. Whole genome and phylogenetic analysis of two SARS-CoV-2 strains isolated in Italy in January and February 2020: additional clues on multiple introductions and further circulation in Europe. <a href="/content/ecdc">Euro Surveill.</a> 2020;25(13):pii=2000305. <a href="https://doi.org/10.2807/1560-7917.ES.2020.25.13.2000305" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2020.25.13.2000305</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 13 Mar 2020;&nbsp;&nbsp; <span class="generated">Accepted</span>: 02 Apr 2020 </span> </p>
/content/10.2807/1560-7917.ES.2020.25.13.2000305
/content/10.2807/1560-7917.ES.2020.25.13.2000305
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