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Abstract

Background

is the main cause of bacterial gastroenteritis worldwide. The main transmission route is through consumption of food contaminated with species or contact with infected animals. In Latvia, the prevalence of campylobacteriosis is reported to be low (4.6 cases per 100,000 population in 2016).

Aim

To determine prevalence, species spectrum and antimicrobial resistance (AMR) of spp. in Latvia, using data from various livestock and human clinical samples.

Methods

We analysed data of microbiological monitoring and AMR (2008 and 2014–16) in Latvia. Data from broilers, poultry, pigs, calves and humans were used to determine prevalence of . Additionally, 45 different origin isolates (22 human) were sequenced on the Illumina MiSeq platform; for each isolate core genome multilocus sequence typing was used and relevant antimicrobial resistance mechanisms were identified.

Results

Overall, prevalence in was 83.3% in pigs, 50.2% in broilers, 16.1% in calves and 5.3% in humans; was the predominant species in all sources except pigs where was main species. High level of resistance in were observed against fluoroquinolones, tetracycline and streptomycin, in most of sequenced isolates genetic determinants of relevant AMR profiles were identified.

Conclusions

In Latvia, prevalence of in livestock is high, especially in pigs and broilers; prevalence in poultry and humans were lower than in other European countries. AMR analysis reveals increase of streptomycin and tetracycline resistant broiler origin strains. WGS demonstrates a high compliance between resistance phenotype and genotype for quinolones and tetracyclines.

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/content/10.2807/1560-7917.ES.2019.24.31.1800357
2019-08-01
2024-11-17
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2019.24.31.1800357
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Campylobacter species prevalence, characterisation of antimicrobial resistance and analysis of whole-genome sequence of isolates from livestock and humans, Latvia, 2008 to 2016
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Ir%C4%93na+Meistere&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Meistere Irēna</a>, <a href="/search?value1=Juris+%C4%B6ibilds&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ķibilds Juris</a>, <a href="/search?value1=L%C4%81sma+Egl%C4%ABte&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Eglīte Lāsma</a>, <a href="/search?value1=Laura+Alksne&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Alksne Laura</a>, <a href="/search?value1=Je%C4%BCena+Avsejenko&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Avsejenko Jeļena</a>, <a href="/search?value1=Alla+Cibrovska&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cibrovska Alla</a>, <a href="/search?value1=Svetlana+Makarova&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Makarova Svetlana</a>, <a href="/search?value1=Madara+Streiki%C5%A1a&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Streikiša Madara</a>, <a href="/search?value1=Lelde+Granti%C5%86a-Ievi%C5%86a&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Grantiņa-Ieviņa Lelde</a>, <a href="/search?value1=Aivars+B%C4%93rzi%C5%86%C5%A1&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bērziņš Aivars</a></span>. Campylobacter species prevalence, characterisation of antimicrobial resistance and analysis of whole-genome sequence of isolates from livestock and humans, Latvia, 2008 to 2016. <a href="/content/ecdc">Euro Surveill.</a> 2019;24(31):pii=1800357. <a href="https://doi.org/10.2807/1560-7917.ES.2019.24.31.1800357" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2019.24.31.1800357</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 03 Jul 2018;&nbsp;&nbsp; <span class="generated">Accepted</span>: 25 Mar 2019 </span> </p>
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