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Abstract

Background

Belgium is a low-endemic country for hepatitis B. Universal hepatitis B vaccination in infants with catch-up in the age cohort of 10–13 year-olds began in 1999.

Aims

Our objective was to evaluate the effect of prevention and control strategies on acute hepatitis B notification rates in Flanders (Belgium) from 2009 to 2017.

Methods

This observational study collected demographic data and risk factors for acute hepatitis B from mandatory notifications to the Agency for Care and Health.

Results

In Flanders, acute hepatitis B notification rates per 100,000 population decreased from 1.6 in 2009 to 0.7 in 2017. These rates declined in all age groups: 0–4-year-olds: 0.6 to 0.0, 5–14-year-olds: 0.2 to 0.0, 15–24-year-olds: 0.8 to 0.7, 25–34-year-olds: 3.4 to 1.1 and ≥ 35-year-olds: 1.59 to 0.7. There was also a downward trend in acute hepatitis B notification rates in native Belgians and first-generation migrants. Among 15–24-year-olds and 25–34-year-olds, a possible reversal of the decreasing trend was observed in 2016 and 2015, respectively. Among 548 acute hepatitis B cases, the main route of transmission was sexual activity (30.7%), and the pattern of transmission routes over time showed an increasing proportion of sexual transmission in men who have sex with men (MSM) after 2014. During the period from 2009 to 2017, five mother-to-child transmissions were reported.

Conclusions

Prevention and control strategies were effective in reducing the acute hepatitis B notification rate. However, stronger prevention and control measures are needed in adult risk groups, particularly MSM.

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/content/10.2807/1560-7917.ES.2019.24.30.1900064
2019-07-25
2024-11-08
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2019.24.30.1900064
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Acute hepatitis B notification rates in Flanders, Belgium, 2009 to 2017
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=%C3%96zg%C3%BCr++Koc&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Koc Özgür </a>, <a href="/search?value1=Pierre+Van+Damme&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Van Damme Pierre</a>, <a href="/search?value1=Dana+Busschots&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Busschots Dana</a>, <a href="/search?value1=Rob+Bielen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bielen Rob</a>, <a href="/search?value1=Anmarie+Forier&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Forier Anmarie</a>, <a href="/search?value1=Frederik+Nevens&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nevens Frederik</a>, <a href="/search?value1=Geert+Robaeys&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Robaeys Geert</a></span>. Acute hepatitis B notification rates in Flanders, Belgium, 2009 to 2017. <a href="/content/ecdc">Euro Surveill.</a> 2019;24(30):pii=1900064. <a href="https://doi.org/10.2807/1560-7917.ES.2019.24.30.1900064" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2019.24.30.1900064</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 21 Jan 2019;&nbsp;&nbsp; <span class="generated">Accepted</span>: 01 Apr 2019 </span> </p>
/content/10.2807/1560-7917.ES.2019.24.30.1900064
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