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Abstract

In September 2018, a child who had returned from Somalia to Germany presented with cutaneous diphtheria by toxigenic biovar The child’s sibling had superinfected insect bites harbouring also toxigenic . Next generation sequencing (NGS) revealed the same strain in both patients suggesting very recent human-to-human transmission. Epidemiological and NGS data suggest that the two cutaneous diphtheria cases constitute the first outbreak by toxigenic in Germany since the 1980s.

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/content/10.2807/1560-7917.ES.2019.24.2.1800683
2019-01-10
2024-12-21
/content/10.2807/1560-7917.ES.2019.24.2.1800683
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Whole genome sequencing suggests transmission of Corynebacterium diphtheriae-caused cutaneous diphtheria in two siblings, Germany, 2018
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Anja+Berger&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Berger Anja</a>, <a href="/search?value1=Alexandra+Dangel&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Dangel Alexandra</a>, <a href="/search?value1=Tilmann+Schober&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Schober Tilmann</a>, <a href="/search?value1=Birgit+Schmidbauer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Schmidbauer Birgit</a>, <a href="/search?value1=Regina+Konrad&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Konrad Regina</a>, <a href="/search?value1=Durdica+Marosevic&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Marosevic Durdica</a>, <a href="/search?value1=S%C3%B6ren+Schubert&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Schubert Sören</a>, <a href="/search?value1=Stefan+H%C3%B6rmansdorfer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hörmansdorfer Stefan</a>, <a href="/search?value1=Nikolaus+Ackermann&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ackermann Nikolaus</a>, <a href="/search?value1=Johannes+H%C3%BCbner&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hübner Johannes</a>, <a href="/search?value1=Andreas+Sing&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sing Andreas</a></span>. Whole genome sequencing suggests transmission of Corynebacterium diphtheriae-caused cutaneous diphtheria in two siblings, Germany, 2018. <a href="/content/ecdc">Euro Surveill.</a> 2019;24(2):pii=1800683. <a href="https://doi.org/10.2807/1560-7917.ES.2019.24.2.1800683" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2019.24.2.1800683</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 21 Dec 2018;&nbsp;&nbsp; <span class="generated">Accepted</span>: 10 Jan 2019 </span> </p>
/content/10.2807/1560-7917.ES.2019.24.2.1800683
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