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Abstract

We describe a multidrug-resistant urethritis case with ceftriaxone resistance and azithromycin intermediate resistance in a heterosexual man in Ireland, August 2018. Whole-genome sequencing showed that the isolate IR72 belongs to the internationally spreading multidrug-resistant ceftriaxone-resistant FC428 clade, initially described in Japan in 2015. IR72 was assigned MSLT ST1903, NG-MAST ST17842 and NG-STAR type 1133, including the ceftriaxone resistance-mediating 60.001. Global awareness of spreading ceftriaxone-resistant gonococcal strains that threaten recommended dual therapies is essential.

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/content/10.2807/1560-7917.ES.2018.23.47.1800617
2018-11-22
2024-12-30
/content/10.2807/1560-7917.ES.2018.23.47.1800617
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Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Daniel+Golparian&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Golparian Daniel</a>, <a href="/search?value1=Lisa+Rose&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rose Lisa</a>, <a href="/search?value1=Almida+Lynam&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lynam Almida</a>, <a href="/search?value1=Aia+Mohamed&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mohamed Aia</a>, <a href="/search?value1=Beatrice+Bercot&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bercot Beatrice</a>, <a href="/search?value1=Makoto+Ohnishi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ohnishi Makoto</a>, <a href="/search?value1=Brendan+Crowley&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Crowley Brendan</a>, <a href="/search?value1=Magnus+Unemo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Unemo Magnus</a></span>. Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018. <a href="/content/ecdc">Euro Surveill.</a> 2018;23(47):pii=1800617. <a href="https://doi.org/10.2807/1560-7917.ES.2018.23.47.1800617" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2018.23.47.1800617</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 12 Nov 2018;&nbsp;&nbsp; <span class="generated">Accepted</span>: 22 Nov 2018 </span> </p>
/content/10.2807/1560-7917.ES.2018.23.47.1800617
/content/10.2807/1560-7917.ES.2018.23.47.1800617
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