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Abstract

An upsurge in Echovirus 30 (E30) infections, associated with meningitis/meningoencephalitis, has been observed in Denmark, Germany, the Netherlands, Norway and Sweden in the period April to September 2018, compared with 2015–2017. In total, 658 E30 infections among 4,537 enterovirus infections were detected in 15 countries between January and September 2018 and affected mainly newborns and 26–45 year-olds. National public health institutes are reminded to remain vigilant and inform clinicians of the ongoing epidemic.

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/content/10.2807/1560-7917.ES.2018.23.44.1800537
2018-11-01
2024-11-23
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2018.23.44.1800537
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References

  1. Norwegian Institute of Public Health. Økning av enterovirus-infeksjoner i juni. [Increase in enterovirus infections in June]. Oslo: Folkehelseinstituttet; 2018. Norwegian. Available from: https://www.fhi.no/nyheter/2018/okning-av-enterovirus-infeksjoner-i-juni/
  2. Medische Microbiologie West-Brabant en Zeeland (Microvida). Start van het enterovirus seizoen. [Start of the enterovirus season]. Breda: Microvida; 2018. Dutch. Available from: http://www.microvida.nl/algemeen/start-van-het-enterovirus-seizoen/
  3. Harvala H, Jasir A, Penttinen P, Pastore Celentano L, Greco D, Broberg E. Surveillance and laboratory detection for non-polio enteroviruses in the European Union/European Economic Area, 2016. Euro Surveill. 2017;22(45):16-00807.  https://doi.org/10.2807/1560-7917.ES.2017.22.45.16-00807  PMID: 29162204 
  4. European Centre for Disease Prevention and Control (ECDC). Data quality monitoring and surveillance system evaluation – A handbook of methods and applications. Stockholm: ECDC; 2014. Available from: https://ecdc.europa.eu/sites/portal/files/media/en/publications/Publications/Data-quality-monitoring-surveillance-system-evaluation-Sept-2014.pdf
  5. Nix WA, Oberste MS, Pallansch MA. Sensitive, seminested PCR amplification of VP1 sequences for direct identification of all enterovirus serotypes from original clinical specimens. J Clin Microbiol. 2006;44(8):2698-704.  https://doi.org/10.1128/JCM.00542-06  PMID: 16891480 
  6. Trallero G, Casas I, Tenorio A, Echevarria JE, Castellanos A, Lozano A, et al. Enteroviruses in Spain: virological and epidemiological studies over 10 years (1988-97). Epidemiol Infect. 2000;124(3):497-506.  https://doi.org/10.1017/S0950268899003726  PMID: 10982074 
  7. Centers for Disease Control and Prevention (CDC). Outbreaks of aseptic meningitis associated with echoviruses 9 and 30 and preliminary surveillance reports on enterovirus activity--United States, 2003. MMWR Morb Mortal Wkly Rep. 2003;52(32):761-4. PMID: 12917581 
  8. Vestergaard HT, Johnsen CK, Böttiger B. An unusual enterovirus outbreak in Denmark: clinical characteristics and molecular epidemiology. Scand J Infect Dis. 2004;36(11-12):840-7.  https://doi.org/10.1080/00365540410021153  PMID: 15764171 
  9. Zhao YN, Jiang QW, Jiang RJ, Chen L, Perlin DS. Echovirus 30, Jiangsu Province, China. Emerg Infect Dis. 2005;11(4):562-7.  https://doi.org/10.3201/eid1104.040995  PMID: 15829194 
  10. Dos Santos GP, Skraba I, Oliveira D, Lima AA, de Melo MM, Kmetzsch CI, et al. Enterovirus meningitis in Brazil, 1998-2003. J Med Virol. 2006;78(1):98-104.  https://doi.org/10.1002/jmv.20509  PMID: 16299728 
  11. Hauri AM, Schimmelpfennig M, Walter-Domes M, Letz A, Diedrich S, Lopez-Pila J, et al. An outbreak of viral meningitis associated with a public swimming pond. Epidemiol Infect. 2005;133(2):291-8.  https://doi.org/10.1017/S0950268804003437  PMID: 15816154 
  12. McWilliam Leitch EC, Bendig J, Cabrerizo M, Cardosa J, Hyypiä T, Ivanova OE, et al. Transmission networks and population turnover of echovirus 30. J Virol. 2009;83(5):2109-18.  https://doi.org/10.1128/JVI.02109-08  PMID: 19091869 
  13. Khetsuriani N, Lamonte-Fowlkes A, Oberst S, Pallansch MA, Centers for Disease Control and Prevention. Enterovirus surveillance--United States, 1970-2005. MMWR Surveill Summ. 2006;55(8):1-20. PMID: 16971890 
  14. Ortner B, Huang CW, Schmid D, Mutz I, Wewalka G, Allerberger F, et al. Epidemiology of enterovirus types causing neurological disease in Austria 1999-2007: detection of clusters of echovirus 30 and enterovirus 71 and analysis of prevalent genotypes. J Med Virol. 2009;81(2):317-24.  https://doi.org/10.1002/jmv.21374  PMID: 19107980 
  15. Trallero G, Avellon A, Otero A, De Miguel T, Pérez C, Rabella N, et al. Enteroviruses in Spain over the decade 1998-2007: virological and epidemiological studies. J Clin Virol. 2010;47(2):170-6.  https://doi.org/10.1016/j.jcv.2009.11.013  PMID: 20007023 
  16. Lévêque N, Jacques J, Renois F, Antona D, Abely M, Chomel JJ, et al. Phylogenetic analysis of Echovirus 30 isolated during the 2005 outbreak in France reveals existence of multiple lineages and suggests frequent recombination events. J Clin Virol. 2010;48(2):137-41.  https://doi.org/10.1016/j.jcv.2010.03.011  PMID: 20381415 
  17. Rudolph H, Prieto Dernbach R, Walka M, Rey-Hinterkopf P, Melichar V, Muschiol E, et al. Comparison of clinical and laboratory characteristics during two major paediatric meningitis outbreaks of echovirus 30 and other non-polio enteroviruses in Germany in 2008 and 2013. Eur J Clin Microbiol Infect Dis. 2017;36(9):1651-60.  https://doi.org/10.1007/s10096-017-2979-7  PMID: 28409290 
  18. Österback R, Kalliokoski T, Lähdesmäki T, Peltola V, Ruuskanen O, Waris M. Echovirus 30 meningitis epidemic followed by an outbreak-specific RT-qPCR. J Clin Virol. 2015;69:7-11.  https://doi.org/10.1016/j.jcv.2015.05.012  PMID: 26209368 
  19. Savolainen-Kopra C, Paananen A, Blomqvist S, Klemola P, Simonen ML, Lappalainen M, et al. A large Finnish echovirus 30 outbreak was preceded by silent circulation of the same genotype. Virus Genes. 2011;42(1):28-36.  https://doi.org/10.1007/s11262-010-0536-x  PMID: 20960045 
  20. Perevoscikovs J, Brila A, Firstova L, Komarova T, Lucenko I, Osmjana J, et al. Ongoing outbreak of aseptic meningitis in South-Eastern Latvia, June - August 2010. Euro Surveill. 2010;15(32):19639. PMID: 20738995 
  21. Cosić G, Durić P, Milosević V, Dekić J, Canak G, Turkulov V. Ongoing outbreak of aseptic meningitis associated with echovirus type 30 in the City of Novi Sad, Autonomous Province of Vojvodina, Serbia, June - July 2010. Euro Surveill. 2010;15(32):19638. PMID: 20738996 
  22. Mantadakis E, Pogka V, Voulgari-Kokota A, Tsouvala E, Emmanouil M, Kremastinou J, et al. Echovirus 30 outbreak associated with a high meningitis attack rate in Thrace, Greece. Pediatr Infect Dis J. 2013;32(8):914-6. PMID: 23459085 
  23. Nougairede A, Bessaud M, Thiberville SD, Piorkowski G, Ninove L, Zandotti C, et al. Widespread circulation of a new echovirus 30 variant causing aseptic meningitis and non-specific viral illness, South-East France, 2013. J Clin Virol. 2014;61(1):118-24.  https://doi.org/10.1016/j.jcv.2014.05.022  PMID: 24973284 
  24. Kee F, McElroy G, Stewart D, Coyle P, Watson J. A community outbreak of echovirus infection associated with an outdoor swimming pool. J Public Health Med. 1994;16(2):145-8.  https://doi.org/10.1093/oxfordjournals.pubmed.a042949  PMID: 7946487 
  25. Faustini A, Fano V, Muscillo M, Zaniratti S, La Rosa G, Tribuzi L, et al. An outbreak of aseptic meningitis due to echovirus 30 associated with attending school and swimming in pools. Int J Infect Dis. 2006;10(4):291-7.  https://doi.org/10.1016/j.ijid.2005.06.008  PMID: 16458563 
  26. Rice SK, Heinl RE, Thornton LL, Opal SM. Clinical characteristics, management strategies, and cost implications of a statewide outbreak of enterovirus meningitis. Clin Infect Dis. 1995;20(4):931-7.  https://doi.org/10.1093/clinids/20.4.931  PMID: 7795097 
  27. Harvala H, Broberg E, Benschop K, Berginc N, Ladhani S, Susi P, et al. Recommendations for enterovirus diagnostics and characterisation within and beyond Europe. J Clin Virol. 2018;101:11-7.  https://doi.org/10.1016/j.jcv.2018.01.008  PMID: 29414181 
  28. Thoelen I, Moës E, Lemey P, Mostmans S, Wollants E, Lindberg AM, et al. Analysis of the serotype and genotype correlation of VP1 and the 5′ noncoding region in an epidemiological survey of the human enterovirus B species. J Clin Microbiol. 2004;42(3):963-71.  https://doi.org/10.1128/JCM.42.3.963-971.2004  PMID: 15004039 
  29. Nasri D, Bouslama L, Omar S, Saoudin H, Bourlet T, Aouni M, et al. Typing of human enterovirus by partial sequencing of VP2. J Clin Microbiol. 2007;45(8):2370-9.  https://doi.org/10.1128/JCM.00093-07  PMID: 17537940 
  30. Böttcher S, Prifert C, Weißbrich B, Adams O, Aldabbagh S, Eis-Hübinger AM, et al. Detection of enterovirus D68 in patients hospitalised in three tertiary university hospitals in Germany, 2013 to 2014. Euro Surveill. 2016;21(19):30227.  https://doi.org/10.2807/1560-7917.ES.2016.21.19.30227  PMID: 27195917 
  31. Cabrerizo M, Echevarria JE, González I, de Miguel T, Trallero G. Molecular epidemiological study of HEV-B enteroviruses involved in the increase in meningitis cases occurred in Spain during 2006. J Med Virol. 2008;80(6):1018-24.  https://doi.org/10.1002/jmv.21197  PMID: 18428125 
Upsurge in echovirus 30 detections in five EU/EEA countries, April to September, 2018
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Eeva+K+Broberg&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Broberg Eeva K</a>, <a href="/search?value1=Benedetto+Simone&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Simone Benedetto</a>, <a href="/search?value1=Josep+Jansa&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Jansa Josep</a>, <a href="/search?value1=the+EU%2FEEA+Member+State+contributors&option1=author&noRedirect=true" class="nonDisambigAuthorLink">the EU/EEA Member State contributors</a></span>. Upsurge in echovirus 30 detections in five EU/EEA countries, April to September, 2018. <a href="/content/ecdc">Euro Surveill.</a> 2018;23(44):pii=1800537. <a href="https://doi.org/10.2807/1560-7917.ES.2018.23.44.1800537" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2018.23.44.1800537</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 02 Oct 2018;&nbsp;&nbsp; <span class="generated">Accepted</span>: 30 Oct 2018 </span> </p>
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