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Abstract

Background and aims

The Burden of Communicable Diseases in Europe (BCoDE) study aimed to calculate disability-adjusted life years (DALYs) for 31 selected diseases in the European Union (EU) and European Economic Area (EEA). DALYs were estimated using an incidence-based and pathogen-based approach. Incidence was estimated through assessment of data availability and quality, and a correction was applied for under-estimation. Calculation of DALYs was performed with the BCoDE software toolkit without applying time discounting and age-weighting. We estimated that one in 14 inhabitants experienced an infectious disease episode for a total burden of 1.38 million DALYs (95% uncertainty interval (UI): 1.25–1.5) between 2009 and 2013; 76% of which was related to the acute phase of the infection and its short-term complications. Influenza had the highest burden (30% of the total burden), followed by tuberculosis, human immunodeficiency virus (HIV) infection/AIDS and invasive pneumococcal disease (IPD). Men had the highest burden measured in DALYs (60% of the total), adults 65 years of age and over had 24% and children less than 5 years of age had 11%. Age group-specific burden showed that infants (less than 1 year of age) and elderly people (80 years of age and over) experienced the highest burden. These results provide baseline estimates for evaluating infectious disease prevention and control strategies. The study promotes an evidence-based approach to describing population health and assessing surveillance data availability and quality, and provides information for the planning and prioritisation of limited resources in infectious disease prevention and control.

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2018-04-19
2024-12-03
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Impact of infectious diseases on population health using incidence-based disability-adjusted life years (DALYs): results from the Burden of Communicable Diseases in Europe study, European Union and European Economic Area countries, 2009 to 2013
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Alessandro+Cassini&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cassini Alessandro</a>, <a href="/search?value1=Edoardo+Colzani&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Colzani Edoardo</a>, <a href="/search?value1=Alessandro+Pini&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pini Alessandro</a>, <a href="/search?value1=Marie-Josee+J+Mangen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mangen Marie-Josee J</a>, <a href="/search?value1=Dietrich+Plass&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Plass Dietrich</a>, <a href="/search?value1=Scott+A+McDonald&option1=author&noRedirect=true" class="nonDisambigAuthorLink">McDonald Scott A</a>, <a href="/search?value1=Guido+Maringhini&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Maringhini Guido</a>, <a href="/search?value1=Alies+van+Lier&option1=author&noRedirect=true" class="nonDisambigAuthorLink">van Lier Alies</a>, <a href="/search?value1=Juanita+A+Haagsma&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Haagsma Juanita A</a>, <a href="/search?value1=Arie+H+Havelaar&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Havelaar Arie H</a>, <a href="/search?value1=Piotr+Kramarz&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kramarz Piotr</a>, <a href="/search?value1=Mirjam+E+Kretzschmar&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kretzschmar Mirjam E</a>, <a href="/search?value1=on+behalf+of+the+BCoDE+consortium&option1=author&noRedirect=true" class="nonDisambigAuthorLink">on behalf of the BCoDE consortium</a></span>. Impact of infectious diseases on population health using incidence-based disability-adjusted life years (DALYs): results from the Burden of Communicable Diseases in Europe study, European Union and European Economic Area countries, 2009 to 2013. <a href="/content/ecdc">Euro Surveill.</a> 2018;23(16):pii=17-00454. <a href="https://doi.org/10.2807/1560-7917.ES.2018.23.16.17-00454" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2018.23.16.17-00454</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 06 Jul 2017;&nbsp;&nbsp; <span class="generated">Accepted</span>: 15 Nov 2017 </span> </p>
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    • Supplement 2. Criteria used when selecting pathogens/diseases

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    • Supplement 1. Disease models – Outcome trees

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    • Supplement 3. Incidence of selected diseases

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    • Supplement 4. Detailed results by disease

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