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Abstract

Introduction

Expanding access to HIV antiretroviral treatment is expected to decrease HIV incidence and acquired immunodeficiency syndrome (AIDS) mortality. However, this may also result in increased HIV drug resistance (DR). Better monitoring and surveillance of HIV DR is required to inform treatment regimens and maintain the long term effectiveness of antiretroviral drugs. As there is currently no formal European Union (EU)-wide collection of HIV DR data, this study aimed to assess the current HIV molecular surveillance capacity in EU/European Economic Area (EEA) countries in order to inform the planning of HIV DR monitoring at EU level. Thirty EU/EEA countries were invited to participate in a survey on HIV molecular surveillance capacity, which also included laboratory aspects. Among 21 responding countries, 13 reported using HIV sequence data (subtype and/or DR) for surveillance purposes at national level. Of those, nine stated that clinical, epidemiological and sequence data were routinely linked for analysis. : We identified similarities between existing HIV molecular surveillance systems, but also found important challenges including human resources, data ownership and legal issues that would need to be addressed.Information on capacities should allow better planning of the phased introduction of HIV DR surveillance at EU/EEA level.

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/content/10.2807/1560-7917.ES.2017.22.49.17-00269
2017-12-07
2024-11-22
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2017.22.49.17-00269
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Assessment of HIV molecular surveillance capacity in the European Union, 2016
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Patrick+Keating&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Keating Patrick</a>, <a href="/search?value1=Anastasia+Pharris&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pharris Anastasia</a>, <a href="/search?value1=Katrin+Leitmeyer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Leitmeyer Katrin</a>, <a href="/search?value1=Stefania+De+Angelis&option1=author&noRedirect=true" class="nonDisambigAuthorLink">De Angelis Stefania</a>, <a href="/search?value1=Annemarie+Wensing&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wensing Annemarie</a>, <a href="/search?value1=Andrew+J+Amato-Gauci&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Amato-Gauci Andrew J</a>, <a href="/search?value1=Eeva+Broberg&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Broberg Eeva</a></span>. Assessment of HIV molecular surveillance capacity in the European Union, 2016. <a href="/content/ecdc">Euro Surveill.</a> 2017;22(49):pii=17-00269. <a href="https://doi.org/10.2807/1560-7917.ES.2017.22.49.17-00269" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2017.22.49.17-00269</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 13 Apr 2017;&nbsp;&nbsp; <span class="generated">Accepted</span>: 19 Sept 2017 </span> </p>
/content/10.2807/1560-7917.ES.2017.22.49.17-00269
/content/10.2807/1560-7917.ES.2017.22.49.17-00269
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