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Abstract

Carbapenems belong to the group of last resort antibiotics in human medicine. Therefore, the emergence of growing numbers of carbapenemase-producing bacteria in food-producing animals or the environment is worrying and an important concern for the public health sector. In the present study, a set of 45 Enterobacteriaceae isolated from German retail seafood (clams and shrimps), sampled in 2016, were investigated by real-time PCR for the presence of carbapenemase-producing bacteria. One (ST10), isolated from a Venus clam () harvested in the Mediterranean Sea (Italy), contained the carbapenemase gene as part of the variable region of a class I integron. Whole-genome sequencing indicated that the integron was embedded in a Tn3-like transposon that also contained the fluoroquinolone resistance gene S1. Additional resistance genes such as the extended-spectrum beta-lactamase and the AmpC gene were also present in this isolate. Except , all resistance genes were located on an IncY plasmid. These results confirm previous observations that carbapenemase-producing bacteria have reached the food chain and are of increasing concern for public health.

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2017-10-26
2024-11-05
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2017.22.43.17-00032
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VIM-1 carbapenemase-producing Escherichia coli isolated from retail seafood, Germany 2016
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Nicole+Roschanski&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Roschanski Nicole</a>, <a href="/search?value1=Sebastian+Guenther&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Guenther Sebastian</a>, <a href="/search?value1=Thi+Thu+Tra+Vu&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Vu Thi Thu Tra</a>, <a href="/search?value1=Jennie+Fischer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fischer Jennie</a>, <a href="/search?value1=Torsten+Semmler&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Semmler Torsten</a>, <a href="/search?value1=Stephan+Huehn&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Huehn Stephan</a>, <a href="/search?value1=Thomas+Alter&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Alter Thomas</a>, <a href="/search?value1=Uwe+Roesler&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Roesler Uwe</a></span>. VIM-1 carbapenemase-producing Escherichia coli isolated from retail seafood, Germany 2016. <a href="/content/ecdc">Euro Surveill.</a> 2017;22(43):pii=17-00032. <a href="https://doi.org/10.2807/1560-7917.ES.2017.22.43.17-00032" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2017.22.43.17-00032</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 10 Jan 2017;&nbsp;&nbsp; <span class="generated">Accepted</span>: 15 May 2017 </span> </p>
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