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Abstract

Healthcare workers (n = 803) with mild symptoms were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (n = 90 positive) and asked to complete a symptom questionnaire. Anosmia, muscle ache, ocular pain, general malaise, headache, extreme tiredness and fever were associated with positivity. A predictive model based on these symptoms showed moderate discriminative value (sensitivity: 91.2%; specificity: 55.6%). While our models would not justify presumptive SARS-CoV-2 diagnosis without molecular confirmation, it can contribute to targeted screening strategies.

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/content/10.2807/1560-7917.ES.2020.25.16.2000508
2020-04-23
2024-11-21
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2020.25.16.2000508
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Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Alma+Tostmann&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Tostmann Alma</a>, <a href="/search?value1=John+Bradley&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bradley John</a>, <a href="/search?value1=Teun+Bousema&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bousema Teun</a>, <a href="/search?value1=Wing-Kee+Yiek&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Yiek Wing-Kee</a>, <a href="/search?value1=Minke+Holwerda&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Holwerda Minke</a>, <a href="/search?value1=Chantal+Bleeker-Rovers&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bleeker-Rovers Chantal</a>, <a href="/search?value1=Jaap+ten+Oever&option1=author&noRedirect=true" class="nonDisambigAuthorLink">ten Oever Jaap</a>, <a href="/search?value1=Corianne+Meijer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Meijer Corianne</a>, <a href="/search?value1=Janette+Rahamat-Langendoen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rahamat-Langendoen Janette</a>, <a href="/search?value1=Joost+Hopman&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hopman Joost</a>, <a href="/search?value1=Nannet+van+der+Geest-Blankert&option1=author&noRedirect=true" class="nonDisambigAuthorLink">van der Geest-Blankert Nannet</a>, <a href="/search?value1=Heiman+Wertheim&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wertheim Heiman</a></span>. Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020. <a href="/content/ecdc">Euro Surveill.</a> 2020;25(16):pii=2000508. <a href="https://doi.org/10.2807/1560-7917.ES.2020.25.16.2000508" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2020.25.16.2000508</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 03 Apr 2020;&nbsp;&nbsp; <span class="generated">Accepted</span>: 21 Apr 2020 </span> </p>
/content/10.2807/1560-7917.ES.2020.25.16.2000508
/content/10.2807/1560-7917.ES.2020.25.16.2000508
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