1887
  1. Home
  2. Eurosurveillance
  3. Volume 22, Issue 47, 23/Nov/2017
  4. Article
Rapid communication Open Access
Like 0
Download

Abstract

For over a decade virtually all A(H3N2) influenza viruses have been resistant to the adamantane class of antivirals. However, during the 2017 influenza season in Australia, 15/461 (3.3%) adamantane-sensitive A(H3N2) viruses encoding serine at residue 31 of the M2 protein were detected, more than the total number identified globally during the last 6 years. A return to wide circulation of adamantane-sensitive A(H3N2) viruses would revive the option of using these drugs for treatment and prophylaxis.

© Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2017.22.47.17-00731
2017-11-23
2024-12-23
/content/10.2807/1560-7917.ES.2017.22.47.17-00731
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/22/47/eurosurv-22-47-1.html?itemId=/content/10.2807/1560-7917.ES.2017.22.47.17-00731&mimeType=html&fmt=ahah

References

  1. Jefferson T, Deeks JJ, Demicheli V, Rivetti D, Rudin M. Amantadine and rimantadine for preventing and treating influenza A in adults. Cochrane Database Syst Rev. 2004; (3):CD001169. PMID: 15266442 
  2. Hayden FG, Hay AJ. Emergence and transmission of influenza A viruses resistant to amantadine and rimantadine. Curr Top Microbiol Immunol. 1992;176:119-30.  https://doi.org/10.1007/978-3-642-77011-1_8  PMID: 1600749 
  3. Ziegler T, Hemphill ML, Ziegler ML, Perez-Oronoz G, Klimov AI, Hampson AW, et al. Low incidence of rimantadine resistance in field isolates of influenza A viruses. J Infect Dis. 1999;180(4):935-9.  https://doi.org/10.1086/314994  PMID: 10479115 
  4. Bright RA, Medina MJ, Xu X, Perez-Oronoz G, Wallis TR, Davis XM, et al. Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern. Lancet. 2005;366(9492):1175-81.  https://doi.org/10.1016/S0140-6736(05)67338-2  PMID: 16198766 
  5. Bright RA, Shay DK, Shu B, Cox NJ, Klimov AI. Adamantane resistance among influenza A viruses isolated early during the 2005-2006 influenza season in the United States. JAMA. 2006;295(8):891-4.  https://doi.org/10.1001/jama.295.8.joc60020  PMID: 16456087 
  6. Deng YM, Spirason N, Iannello P, Jelley L, Lau H, Barr IG. A simplified Sanger sequencing method for full genome sequencing of multiple subtypes of human influenza A viruses. J Clin Virol. 2015;68:43-8.  https://doi.org/10.1016/j.jcv.2015.04.019  PMID: 26071334 
  7. Zhou B, Deng YM, Barnes JR, Sessions O, Chou TW, Wilson M, et al. Multiplex RT-PCR for Simultaneous Surveillance of Influenza A and B Viruses. J Clin Microbiol. 2017 Oct 4. pii: JCM.00957-17. doi:  https://doi.org/10.1128/JCM.00957-17 . PMID: 28978683. [Epub ahead of print].
  8. Deng YM, Caldwell N, Barr IG. Rapid detection and subtyping of human influenza A viruses and reassortants by pyrosequencing. PLoS One. 2011;6(8):e23400.  https://doi.org/10.1371/journal.pone.0023400  PMID: 21886790 
  9. Zaraket H, Kondo H, Hibino A, Yagami R, Odagiri T, Takemae N, et al. Japanese Influenza Collaborative Study Group. Full Genome Characterization of Human Influenza A/H3N2 Isolates from Asian Countries Reveals a Rare Amantadine Resistance-Conferring Mutation and Novel PB1-F2 Polymorphisms. Front Microbiol. 2016;7:262.  https://doi.org/10.3389/fmicb.2016.00262  PMID: 27014195 
  10. Mast EE, Harmon MW, Gravenstein S, Wu SP, Arden NH, Circo R, et al. Emergence and possible transmission of amantadine-resistant viruses during nursing home outbreaks of influenza A (H3N2). Am J Epidemiol. 1991;134(9):988-97.  https://doi.org/10.1093/oxfordjournals.aje.a116184  PMID: 1951297 
  11. Degelau J, Somani SK, Cooper SL, Guay DR, Crossley KB. Amantadine-resistant influenza A in a nursing facility. Arch Intern Med. 1992;152(2):390-2.  https://doi.org/10.1001/archinte.1992.00400140128027  PMID: 1739371 
  12. Hayden FG, Belshe RB, Clover RD, Hay AJ, Oakes MG, Soo W. Emergence and apparent transmission of rimantadine-resistant influenza A virus in families. N Engl J Med. 1989;321(25):1696-702.  https://doi.org/10.1056/NEJM198912213212502  PMID: 2687687 
  13. Houck P, Hemphill M, LaCroix S, Hirsh D, Cox N. Amantadine-resistant influenza A in nursing homes. Identification of a resistant virus prior to drug use. Arch Intern Med. 1995;155(5):533-7.  https://doi.org/10.1001/archinte.1995.00430050113012  PMID: 7864709 
  14. Hall CB, Dolin R, Gala CL, Markovitz DM, Zhang YQ, Madore PH, et al. Children with influenza A infection: treatment with rimantadine. Pediatrics. 1987;80(2):275-82. PMID: 3302925 
  15. Barr IG, Hurt AC, Deed N, Iannello P, Tomasov C, Komadina N. The emergence of adamantane resistance in influenza A(H1) viruses in Australia and regionally in 2006. Antiviral Res. 2007;75(2):173-6.  https://doi.org/10.1016/j.antiviral.2007.01.006  PMID: 17350111 
  16. Barr IG, Deng YM, Iannello P, Hurt AC, Komadina N. Adamantane resistance in influenza A(H1) viruses increased in 2007 in South East Asia but decreased in Australia and some other countries. Antiviral Res. 2008;80(2):200-5.  https://doi.org/10.1016/j.antiviral.2008.06.008  PMID: 18611414 
  17. Simonsen L, Viboud C, Grenfell BT, Dushoff J, Jennings L, Smit M, et al. The genesis and spread of reassortment human influenza A/H3N2 viruses conferring adamantane resistance. Mol Biol Evol. 2007;24(8):1811-20.  https://doi.org/10.1093/molbev/msm103  PMID: 17522084 
  18. Beigel JH, Bao Y, Beeler J, Manosuthi W, Slandzicki A, Dar SM, et al. Oseltamivir, amantadine, and ribavirin combination antiviral therapy versus oseltamivir monotherapy for the treatment of influenza: a multicentre, double-blind, randomised phase 2 trial. Lancet Infect Dis. 2017 Sep 22. pii: S1473-3099(17)30476-0. doi:  https://doi.org/10.1016/S1473-3099(17)30476-0 . [Epub ahead of print]. PMID: 28958678.
Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Aeron+Hurt&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hurt Aeron</a>, <a href="/search?value1=Naomi+Komadina&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Komadina Naomi</a>, <a href="/search?value1=Yi-Mo+Deng&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Deng Yi-Mo</a>, <a href="/search?value1=Matthew+Kaye&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kaye Matthew</a>, <a href="/search?value1=Sheena+Sullivan&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sullivan Sheena</a>, <a href="/search?value1=Kanta+Subbarao&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Subbarao Kanta</a>, <a href="/search?value1=Ian+Barr&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Barr Ian</a></span>. Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?. <a href="/content/ecdc">Euro Surveill.</a> 2017;22(47):pii=17-00731. <a href="https://doi.org/10.2807/1560-7917.ES.2017.22.47.17-00731" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2017.22.47.17-00731</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 03 Nov 2017;&nbsp;&nbsp; <span class="generated">Accepted</span>: 22 Nov 2017 </span> </p>
/content/10.2807/1560-7917.ES.2017.22.47.17-00731
/content/10.2807/1560-7917.ES.2017.22.47.17-00731
Loading

Data & Media loading...

Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error