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Surveillance and outbreak report Open Access
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Abstract

Under the coordination of the European Centre for Disease Prevention and Control (ECDC), the European Legionnaires’ disease Surveillance Network (ELDSNet) conducts surveillance of Legionnaires’ disease (LD) in Europe. Between 2011 and 2015, 29 countries reported 30,532 LD cases to ECDC (28,188 (92.3%) confirmed and 2,344 (7.7%) probable). Four countries (France, Germany, Italy and Spain) accounted for 70.3% of all reported cases, although their combined populations represented only 49.9% of the study population. The age-standardised rate of all cases increased from 0.97 cases/100,000 population in 2011 to 1.30 cases/100,000 population in 2015, corresponding to an annual average increase of 0.09 cases/100,000 population (95%CI 0.02–0.14; p = 0.02). Demographics and infection setting remained unchanged with ca 70% of cases being community-acquired and 80% occurring in people aged 50 years and older. Clinical outcome was known for 23,164 cases, of whom 2,161 (9.3%) died. The overall case fatality ratio decreased steadily from 10.5% in 2011 to 8.1% in 2015, probably reflecting improved reporting completeness. Five countries (Austria, Czech Republic, Germany, Italy, and Norway) had increasing age-standardised LD notification rates over the 2011−15 period, but there was no increase in notification rates in countries where the 2011 rate was below 0.5/100,000 population.

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/content/10.2807/1560-7917.ES.2017.22.27.30566
2017-07-06
2024-04-19
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2017.22.27.30566
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References

  1. Fields BS, Benson RF, Besser RE. Legionella and Legionnaires’ disease: 25 years of investigation. Clin Microbiol Rev. 2002;15(3):506-26.  https://doi.org/10.1128/CMR.15.3.506-526.2002  PMID: 12097254 
  2. Correia AM, Ferreira JS, Borges V, Nunes A, Gomes B, Capucho R, et al. Probable Person-to-Person Transmission of Legionnaires’ Disease. N Engl J Med. 2016;374(5):497-8.  https://doi.org/10.1056/NEJMc1505356  PMID: 26840151 
  3. Beauté J, Zucs P, de Jong BEuropean Legionnaires’ Disease Surveillance Network. Legionnaires disease in Europe, 2009-2010. Euro Surveill. 2013;18(10):20417. PMID: 23515061 
  4. Beauté J, Robesyn E, de Jong BEuropean Legionnaires’ Disease Surveillance Network. Legionnaires’ disease in Europe: all quiet on the eastern front? Eur Respir J. 2013;42(6):1454-8.  https://doi.org/10.1183/09031936.00089113  PMID: 24293418 
  5. Sakamoto R. Legionnaire’s disease, weather and climate. Bull World Health Organ. 2015;93(6):435-6.  https://doi.org/10.2471/BLT.14.142299  PMID: 26240466 
  6. Beauté J, Sandin S, Uldum SA, Rota MC, Brandsema P, Giesecke J, et al. Short-term effects of atmospheric pressure, temperature, and rainfall on notification rate of community-acquired Legionnaires’ disease in four European countries. Epidemiol Infect. 2016;1-11. [Epub ahead of print]. PMID: 27572105 
  7. European Environment Agency (EEA). Climate change, impacts and vulnerability in Europe 2012 an indicator-based report. Luxembourg: EEA; 2012. Available from: http://www.eea.europa.eu/publications/climate-impacts-and-vulnerability-2012/at_download/file
  8. Eurostat. Population structure and ageing - Statistics Explained. Luxembourg: Eurostat. [Accessed 21 Apr 2016]. Available from: http://ec.europa.eu/eurostat/statistics-explained/index.php/Population_structure_and_ageing
  9. Campese C, Jarraud S, Sommen C, Maine C, Che D. Legionnaires’ disease in France: sensitivity of the mandatory notification has improved over the last decade. Epidemiol Infect. 2013;141(12):2644-9.  https://doi.org/10.1017/S0950268813000502  PMID: 23481220 
  10. Commission of the European Communities. Commission Implementing Decision 2012/506/EU of 8 August 2012 amending Decision 2002/253/EC laying down case definitions for reporting communicable diseases to the Community network under Decision No 2119/98/EC of the European Parliament and of the Council. Luxembourg: Official Journal of the European Union. Available from: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2012:262:0001:0057:EN:PDF
  11. Eurostat. Population on 1 January by age group and sex. Luxembourg: Eurostat. [Accessed 10 Aug 2016]. Available from: http://appsso.eurostat.ec.europa.eu/nui/show.do?dataset=demo_pjangroup&lang=en
  12. Boyle P, Parkin DM. Cancer registration: principles and methods. Statistical methods for registries. IARC Sci Publ. 1991; (95):126-58. PMID: 1894318 
  13. Brandsema PS, Euser SM, Karagiannis I, Den Boer JW, Van Der Hoek W. Summer increase of Legionnaires’ disease 2010 in The Netherlands associated with weather conditions and implications for source finding. Epidemiol Infect. 2014;142(11):2360-71.  https://doi.org/10.1017/S0950268813003476  PMID: 24576486 
  14. Dooling KL, Toews K-A, Hicks LA, Garrison LE, Bachaus B, Zansky S, et al. Active Bacterial Core Surveillance for Legionellosis - United States, 2011-2013. MMWR Morb Mortal Wkly Rep. 2015;64(42):1190-3.  https://doi.org/10.15585/mmwr.mm6442a2  PMID: 26513329 
  15. Rota MC, Caporali MG, Bella A, Ricci ML, Napoli C. Legionnaires’ disease in Italy: results of the epidemiological surveillance from 2000 to 2011. Euro Surveill. 2013;18(23):20497. PMID: 23787129 
  16. Rozentale B, Bormane A, Perevosčikovs J, Lucenko I, Brila A. Increase of cases of legionellosis in Latvia, 2011. Euro Surveill. 2011;16(45):20009. PMID: 22114976 
  17. Beauté J, Zucs P, de Jong B. Risk for travel-associated legionnaires’ disease, Europe, 2009. Emerg Infect Dis. 2012;18(11):1811-6.  https://doi.org/10.3201/eid1811.120496  PMID: 23092591 
  18. Tomova I, Marinov R, Maeva I. First cluster of travel-associated legionnaires’ disease detected in Bulgarian citizens. Euro Surveill. 2007;12(4):E070412.2. PMID: 17439804 
  19. Stypułkowska-Misiurewicz H, Czerwiński MA. Legionellosis in Poland in 2014. Przegl Epidemiol. 2016;70(2):203-7. PMID: 27779835 
  20. Vanaclocha H, Guiral S, Morera V, Calatayud MA, Castellanos M, Moya V, et al. Preliminary report: outbreak of Legionnaires disease in a hotel in Calp, Spain, update on 22 February 2012. Euro Surveill. 2012;17(8):20093. PMID: 22401506 
  21. Irons JF, Dunn MJG, Kefala K, Thorn S, Lakha F, Caesar D, et al. The effect of a large Legionnaires’ disease outbreak in Southwest Edinburgh on acute and critical care services. QJM. 2013;106(12):1087-94.  https://doi.org/10.1093/qjmed/hct167  PMID: 23970183 
  22. Maisa A, Brockmann A, Renken F, Lück C, Pleischl S, Exner M, et al. Epidemiological investigation and case-control study: a Legionnaires’ disease outbreak associated with cooling towers in Warstein, Germany, August-September 2013. Euro Surveill. 2015;20(46):30064.  https://doi.org/10.2807/1560-7917.ES.2015.20.46.30064  PMID: 26607018 
  23. Shivaji T, Sousa Pinto C, San-Bento A, Oliveira Serra LA, Valente J, Machado J, et al. A large community outbreak of Legionnaires disease in Vila Franca de Xira, Portugal, October to November 2014. Euro Surveill. 2014;19(50):20991.  https://doi.org/10.2807/1560-7917.ES2014.19.50.20991  PMID: 25597540 
  24. Pelaz C, Cano R, Chico M, Asensio G, Bellido B, Iascu A, et al. A large community outbreak of Legionnaires´ disease in Manzanares, Ciudad Real, Spain. 4th ESGLI Conference; 2016; Amsterdam. Available from: http://www.iwcconferences.com/wp-content/uploads/2016/10/Conference-book-ESGLI.pdf
  25. European Centre for Disease Prevention and Control (ECDC). Legionnaires’ disease surveillance in Europe, 2014. Stockholm: ECDC; 2016. Available from: http://ecdc.europa.eu/en/publications/Publications/legionnares-disease-europe-2014.pdf
  26. Organisation for Economic Co-operation and Development (OECD). Non-medical determinants of health. Paris: OECD. [Accessed 26 Oct 2016]. Available from: http://stats.oecd.org/index.aspx?DataSetCode=HEALTH_LVNG
  27. Straus WL, Plouffe JF, File TM Jr, Lipman HB, Hackman BH, Salstrom SJ, et al. Risk factors for domestic acquisition of legionnaires disease. Ohio legionnaires Disease Group. Arch Intern Med. 1996;156(15):1685-92.  https://doi.org/10.1001/archinte.1996.00440140115011  PMID: 8694667 
  28. Begum M, Lewison G, Wright JSF, Pallari E, Sullivan R. European Non-Communicable Respiratory Disease Research, 2002-13: Bibliometric Study of Outputs and Funding. PLoS One. 2016;11(4):e0154197.  https://doi.org/10.1371/journal.pone.0154197  PMID: 27111670 
  29. Farnham A, Alleyne L, Cimini D, Balter S. Legionnaires’ disease incidence and risk factors, New York, New York, USA, 2002-2011. Emerg Infect Dis. 2014;20(11):1795-802.  https://doi.org/10.3201/eid2011.131872  PMID: 25513657 
  30. Greenberg D, Chiou CC, Famigilleti R, Lee TC, Yu VL. Problem pathogens: paediatric legionellosis--implications for improved diagnosis. Lancet Infect Dis. 2006;6(8):529-35.  https://doi.org/10.1016/S1473-3099(06)70553-9  PMID: 16870531 
  31. Phin N, Parry-Ford F, Harrison T, Stagg HR, Zhang N, Kumar K, et al. Epidemiology and clinical management of Legionnaires’ disease. Lancet Infect Dis. 2014;14(10):1011-21.  https://doi.org/10.1016/S1473-3099(14)70713-3  PMID: 24970283 
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