Steep rise in norovirus cases and emergence of a new recombinant strain GII.P16-GII.2, Germany, winter 2016

S Niendorf; S Jacobsen; M Faber; A M Eis-Hübinger; J Hofmann; O Zimmermann; M Höhne; C T Bock

doi:10.2807/1560-7917.ES.2017.22.4.30447

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Steep rise in norovirus cases and emergence of a new recombinant strain GII.P16-GII.2, Germany, winter 2016
S Niendorf^1,2 , S Jacobsen^1,2 , M Faber³ , A M Eis-Hübinger⁴ , J Hofmann⁵ , O Zimmermann⁶ , M Höhne^1,2 , C T Bock¹
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Affiliations: ¹ Department of Infectious Diseases, Robert Koch-Institute, Berlin, Germany ² Consultant Laboratory for Noroviruses, Robert Koch-Institute, Berlin, Germany ³ Department for Infectious Disease Epidemiology, Robert Koch-Institute, Berlin, Germany ⁴ Institute of Virology, University of Bonn Medical Centre, Bonn, Germany ⁵ Institute of Medical Virology, Charité University Medicine, Berlin, and Labor Berlin, Charité-Vivantes GmbH, Berlin, Germany ⁶ Institute of Medical Microbiology, Göttingen, Germany

Correspondence:
Sandra Niendorf
NiendorfS rki.de
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Citation style for this article: Niendorf S, Jacobsen S, Faber M, Eis-Hübinger A M, Hofmann J, Zimmermann O, Höhne M, Bock C T. Steep rise in norovirus cases and emergence of a new recombinant strain GII.P16-GII.2, Germany, winter 2016. Euro Surveill. 2017;22(4):pii=30447. https://doi.org/10.2807/1560-7917.ES.2017.22.4.30447 Received: 20 Dec 2016; Accepted: 25 Jan 2017

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Abstract

Since early November 2016, the number of laboratory-confirmed norovirus infections reported in Germany has been increasing steeply. Here, we report the detection and genetic characterisation of an emerging norovirus recombinant, GII.P16-GII.2. This strain was frequently identified as the cause of sporadic cases as well as outbreaks in nine federal states of Germany. Our findings suggest that the emergence of GII.P16-GII.2 contributed to rising case numbers of norovirus gastroenteritis in Germany.

This work is licensed under a Creative Commons Attribution 4.0 International License.

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References

Ahmed SM, Hall AJ, Robinson AE, Verhoef L, Premkumar P, Parashar UD, et al. Global prevalence of norovirus in cases of gastroenteritis: a systematic review and meta-analysis. Lancet Infect Dis. 2014;14(8):725-30. https://doi.org/10.1016/S1473-3099(14)70767-4 PMID: 24981041
Kroneman A, Vega E, Vennema H, Vinjé J, White PA, Hansman G, et al. Proposal for a unified norovirus nomenclature and genotyping. Arch Virol. 2013;158(10):2059-68. https://doi.org/10.1007/s00705-013-1708-5 PMID: 23615870
de Graaf M, van Beek J, Vennema H, Podkolzin AT, Hewitt J, Bucardo F, et al. Emergence of a novel GII.17 norovirus – End of the GII.4 era? Euro Surveill. 2015;20(26):21178. https://doi.org/10.2807/1560-7917.ES2015.20.26.21178 PMID: 26159308
Bull RA, Eden JS, Rawlinson WD, White PA. Rapid evolution of pandemic noroviruses of the GII.4 lineage. PLoS Pathog. 2010;6(3):e1000831. https://doi.org/10.1371/journal.ppat.1000831 PMID: 20360972
Bruggink L, Catton M, Marshall J. A norovirus intervariant GII.4 recombinant in Victoria, Australia, June 2016: the next epidemic variant? Euro Surveill. 2016;21(39):30353. https://doi.org/10.2807/1560-7917.ES.2016.21.39.30353 PMID: 27719750
Höhne M, Niendorf S, Mas Marques A, Bock CT. Use of sequence analysis of the P2 domain for characterization of norovirus strains causing a large multistate outbreak of norovirus gastroenteritis in Germany 2012. Int J Med Microbiol. 2015;305(7):612-8. https://doi.org/10.1016/j.ijmm.2015.08.010 PMID: 26341330
Bernard H, Höhne M, Niendorf S, Altmann D, Stark K. Epidemiology of norovirus gastroenteritis in Germany 2001-2009: eight seasons of routine surveillance. Epidemiol Infect. 2013;142(1):63-74. https://doi.org/10.1017/S0950268813000435 PMID: 23517686
Han J, Ji L, Shen Y, Wu X, Xu D, Chen L. Emergence and predominance of norovirus GII.17 in Huzhou, China, 2014-2015. Virol J. 2015;12(1):139. https://doi.org/10.1186/s12985-015-0370-9 PMID: 26362650
Matsushima Y, Ishikawa M, Shimizu T, Komane A, Kasuo S, Shinohara M, et al. Genetic analyses of GII.17 norovirus strains in diarrheal disease outbreaks from December 2014 to March 2015 in Japan reveal a novel polymerase sequence and amino acid substitutions in the capsid region. Euro Surveill. 2015;20(26):21173. https://doi.org/10.2807/1560-7917.ES2015.20.26.21173 PMID: 26159307
Iritani N, Kaida A, Abe N, Kubo H, Sekiguchi J, Yamamoto SP, et al. Detection and genetic characterization of human enteric viruses in oyster-associated gastroenteritis outbreaks between 2001 and 2012 in Osaka City, Japan. J Med Virol. 2014;86(12):2019-25. https://doi.org/10.1002/jmv.23883 PMID: 24415518
Wang YH, Zhou DJ, Zhou X, Yang T, Ghosh S, Pang BB, et al. Molecular epidemiology of noroviruses in children and adults with acute gastroenteritis in Wuhan, China, 2007-2010. Arch Virol. 2012;157(12):2417-24. https://doi.org/10.1007/s00705-012-1437-1 PMID: 22886184

Steep rise in norovirus cases and emergence of a new recombinant strain GII.P16-GII.2, Germany, winter 2016

Citation style for this article: <a href="/search?value1=S+Niendorf&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Niendorf S</a>, <a href="/search?value1=S+Jacobsen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Jacobsen S</a>, <a href="/search?value1=M+Faber&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Faber M</a>, <a href="/search?value1=A+M+Eis-H%C3%BCbinger&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Eis-Hübinger A M</a>, <a href="/search?value1=J+Hofmann&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hofmann J</a>, <a href="/search?value1=O+Zimmermann&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zimmermann O</a>, <a href="/search?value1=M+H%C3%B6hne&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Höhne M</a>, <a href="/search?value1=C+T+Bock&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bock C T</a>. Steep rise in norovirus cases and emergence of a new recombinant strain GII.P16-GII.2, Germany, winter 2016. <a href="/content/ecdc">Euro Surveill.</a> 2017;22(4):pii=30447. <a href="https://doi.org/10.2807/1560-7917.ES.2017.22.4.30447" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2017.22.4.30447</a> Received: 20 Dec 2016;   Accepted: 25 Jan 2017

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Steep rise in norovirus cases and emergence of a new recombinant strain GII.P16-GII.2, Germany, winter 2016

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