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Abstract

Respiratory specimens collected from outpatients with influenza-like illness in three Canadian provinces (British Columbia (BC), Alberta and Quebec) participating in a community-based sentinel surveillance network were prospectively screened for enterovirus-D68 (EV-D68) from 1 August to 31 December 2014 and compared to specimens collected from 1 October 2013 to 31 July 2014. Eighteen (1%) of 1,894 specimens were EV-D68-positive: 1/348 (0.3%) collected from October to December 2013 and 11/460 (2.4%) from October to December 2014, an eight-fold increase in detection rates (p=0.01), consistent with epidemic circulation in autumn 2014. The remaining EV-D68 detections were in September 2014 (6/37). Enhanced passive surveillance was also conducted on all inpatient and outpatient EV-D68 cases (n=211) detected at the BC provincial reference laboratory from 28 August to 31 December 2014. Incidence of hospitalisations was 3/100,000 overall and 21, 17, 4 and 1/100,000 among those <5, 5–9, 10–19 and ≥20-years-old with male-to-female ratios >1 among paediatric but not adult cases. Three cases in BC with comorbidity or co-infection died and five exhibited neurological features persisting >9 months. Active surveillance in outpatient and inpatient settings is needed from more areas and additional seasons to better understand EV-D68 epidemiology and potential at-risk groups for severe or unusual manifestations.

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2015-10-29
2024-11-21
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2015.20.43.30047
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Systematic community- and hospital-based surveillance for enterovirus-D68 in three Canadian provinces, August to December 2014
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Danuta+M+Skowronski&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Skowronski Danuta M</a>, <a href="/search?value1=Catharine+Chambers&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Chambers Catharine</a>, <a href="/search?value1=Suzana+Sabaiduc&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sabaiduc Suzana</a>, <a href="/search?value1=Michelle+Murti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Murti Michelle</a>, <a href="/search?value1=Reka+Gustafson&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gustafson Reka</a>, <a href="/search?value1=Sue+Pollock&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pollock Sue</a>, <a href="/search?value1=Dee+Hoyano&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hoyano Dee</a>, <a href="/search?value1=Shirley+Rempel&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rempel Shirley</a>, <a href="/search?value1=Sandra+Allison&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Allison Sandra</a>, <a href="/search?value1=Gaston+De+Serres&option1=author&noRedirect=true" class="nonDisambigAuthorLink">De Serres Gaston</a>, <a href="/search?value1=James+A+Dickinson&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Dickinson James A</a>, <a href="/search?value1=Raymond+Tellier&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Tellier Raymond</a>, <a href="/search?value1=Kevin+Fonseca&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fonseca Kevin</a>, <a href="/search?value1=Steven+J+Drews&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Drews Steven J</a>, <a href="/search?value1=Christine+Martineau&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Martineau Christine</a>, <a href="/search?value1=Francesca+Reyes-Domingo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Reyes-Domingo Francesca</a>, <a href="/search?value1=Tom+Wong&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wong Tom</a>, <a href="/search?value1=Patrick+Tang&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Tang Patrick</a>, <a href="/search?value1=Mel+Krajden&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Krajden Mel</a></span>. Systematic community- and hospital-based surveillance for enterovirus-D68 in three Canadian provinces, August to December 2014. <a href="/content/ecdc">Euro Surveill.</a> 2015;20(43):pii=30047. <a href="https://doi.org/10.2807/1560-7917.ES.2015.20.43.30047" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2015.20.43.30047</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 04 Aug 2015;&nbsp;&nbsp; <span class="generated">Accepted</span>: 04 Oct 2015 </span> </p>
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