Emergence of a novel cluster of influenza A(H5N1) virus clade 2.2.1.2 with putative human health impact in Egypt, 2014/15

A S Arafa; M M Naguib; C Luttermann; A A Selim; W H Kilany; N Hagag; A Samy; A Abdelhalim; M K Hassan; E M Abdelwhab; Y Makonnen; G Dauphin; J Lubroth; T C Mettenleiter; M Beer; C Grund; T C Harder

doi:10.2807/1560-7917.ES2015.20.13.21085

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Emergence of a novel cluster of influenza A(H5N1) virus clade 2.2.1.2 with putative human health impact in Egypt, 2014/15
A S Arafa^1,2 , M M Naguib^1,2,3 , C Luttermann³ , A A Selim¹ , W H Kilany¹ , N Hagag¹ , A Samy¹ , A Abdelhalim¹ , M K Hassan¹ , E M Abdelwhab¹ , Y Makonnen⁴ , G Dauphin⁵ , J Lubroth⁵ , T C Mettenleiter³ , M Beer³ , C Grund³ , T C Harder³
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Affiliations: ¹ National Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Dokki, Giza, Egypt ² These authors have contributed equally ³ Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald Insel-Riems, Germany ⁴ Food and Agriculture Organization of the United Nations (FAO), Emergency Centre for Transboundary animal Diseases (ECTAD), Cairo, Egypt ⁵ Food and Agriculture Organisation of the United Nations (FAO), Animal Production and Health division, Viale delle Terme di Caracalla, Rome, Italy

Correspondence:
T Harder
timm.harder fli.bund.de
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Citation style for this article: Arafa A S, Naguib M M, Luttermann C, Selim A A, Kilany W H, Hagag N, Samy A, Abdelhalim A, Hassan M K, Abdelwhab E M, Makonnen Y, Dauphin G, Lubroth J, Mettenleiter T C, Beer M, Grund C, Harder T C. Emergence of a novel cluster of influenza A(H5N1) virus clade 2.2.1.2 with putative human health impact in Egypt, 2014/15. Euro Surveill. 2015;20(13):pii=21085. https://doi.org/10.2807/1560-7917.ES2015.20.13.21085 Received: 27 Mar 2015

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Abstract

A distinct cluster of highly pathogenic avian influenza viruses of subtype A(H5N1) has been found to emerge within clade 2.2.1.2 in poultry in Egypt since summer 2014 and appears to have quickly become predominant. Viruses of this cluster may be associated with increased incidence of human influenza A(H5N1) infections in Egypt over the last months.