Effectiveness of influenza vaccination programme in preventing hospital admissions, Valencia, 2014/15 early results

J Puig-Barberà; A Mira-Iglesias; M Tortajada-Girbés; F X López-Labrador; A Belenguer-Varea; M Carballido-Fernández; E Carbonell-Franco; C Carratalá-Munuera; R Limón-Ramírez; J Mollar-Maseres; M del Carmen Otero-Reigada; G Schwarz-Chavarri; J Tuells; V Gil-Guillén; for the Valencia Hospital Network for the Study of Influenza and Respiratory Viruses Disease

doi:10.2807/1560-7917.ES2015.20.8.21044

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Effectiveness of influenza vaccination programme in preventing hospital admissions, Valencia, 2014/15 early results
J Puig-Barberà^1,2 , A Mira-Iglesias¹ , M Tortajada-Girbés³ , F X López-Labrador^1,4 , A Belenguer-Varea⁵ , M Carballido-Fernández⁶ , E Carbonell-Franco⁷ , C Carratalá-Munuera^8,9 , R Limón-Ramírez¹⁰ , J Mollar-Maseres¹¹ , M del Carmen Otero-Reigada¹¹ , G Schwarz-Chavarri¹² , J Tuells¹³ , V Gil-Guillén^9,14 , for the Valencia Hospital Network for the Study of Influenza and Respiratory Viruses Disease¹⁵
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Affiliations: ¹ Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO), Valencia, Spain ² Centro de Salud Pública de Castellón, Castellón, Spain ³ Hospital Doctor Peset, Valencia, Spain ⁴ Consorcio de Investigación Biomédica de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain ⁵ Hospital de La Ribera, Alzira, Spain ⁶ Hospital General de Castellón, Spain ⁷ Hospital Arnau de Vilanova, Valencia, Spain ⁸ Hospital San Juan, Alicante, Spain ⁹ Cátedra de Medicina de Familia. Departamento de Medicina Clínica, Universidad Miguel Hernández, San Juan, Alicante, Spain ¹⁰ Hospital de la Plana, Vila-real, Spain ¹¹ Hospital Universitario y Politécnico La Fe, Valencia, Spain ¹² Hospital General de Alicante, Alicante, Spain ¹³ Hospital Universitario del Vinalopó, Elche, Spain ¹⁴ Hospital de Elda, Elda, Spain ¹⁵ The Valencia Hospital Network for the Study of Influenza and Respiratory Virus Disease (VAHNSI) members are listed at the end of the article

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J Puig-Barberà
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Citation style for this article: Puig-Barberà J, Mira-Iglesias A, Tortajada-Girbés M, López-Labrador F X, Belenguer-Varea A, Carballido-Fernández M, Carbonell-Franco E, Carratalá-Munuera C, Limón-Ramírez R, Mollar-Maseres J, del Carmen Otero-Reigada M, Schwarz-Chavarri G, Tuells J, Gil-Guillén V, for the Valencia Hospital Network for the Study of Influenza and Respiratory Viruses Disease. Effectiveness of influenza vaccination programme in preventing hospital admissions, Valencia, 2014/15 early results. Euro Surveill. 2015;20(8):pii=21044. https://doi.org/10.2807/1560-7917.ES2015.20.8.21044 Received: 19 Feb 2015

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Abstract

Preliminary results for the 2014/15 season indicate low to null effect of vaccination against influenza A(H3N2)-related disease. As of week 5 2015, there have been 1,136 hospital admissions, 210 were due to influenza and 98% of subtype A strains were H3. Adjusted influenza vaccine effectiveness was 33% (range: 6-53%) overall and 40% (range: 13% to 59%) in those 65 years and older. Vaccination reduced by 44% (28-68%) the probability of admission with influenza. .