Effectiveness of seasonal influenza vaccination during pregnancy in preventing influenza infection in infants, England, 2013/14

G Dabrera; H Zhao; N Andrews; F Begum; H K Green; J Ellis; K Elias; M Donati; M Zambon; R Pebody

doi:10.2807/1560-7917.ES2014.19.45.20959

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Effectiveness of seasonal influenza vaccination during pregnancy in preventing influenza infection in infants, England, 2013/14
G Dabrera^1,2,3 , H Zhao³ , N Andrews³ , F Begum³ , H K Green³ , J Ellis⁴ , K Elias⁵ , M Donati⁶ , M Zambon⁴ , R Pebody³
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Affiliations: ¹ Field Epidemiology Training Programme, Public Health England, London, United Kingdom ² European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden ³ Centre for Infectious Disease Surveillance and Control, Public Health England, London, United Kingdom ⁴ Virus Reference Department, Microbiology Services, Public Health England, London, United Kingdom ⁵ Coach House Surgery, Watford, United Kingdom ⁶ Public Health England Bristol Public Health Laboratory, Bristol, United Kingdom

Correspondence:
R Pebody
Richard.Pebody phe.gov.uk
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Citation style for this article: Dabrera G, Zhao H, Andrews N, Begum F, Green H K, Ellis J, Elias K, Donati M, Zambon M, Pebody R. Effectiveness of seasonal influenza vaccination during pregnancy in preventing influenza infection in infants, England, 2013/14. Euro Surveill. 2014;19(45):pii=20959. https://doi.org/10.2807/1560-7917.ES2014.19.45.20959 Received: 04 Nov 2014

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Abstract

In this study we used the screening method to estimate the effectiveness of seasonal influenza vaccination during pregnancy in preventing influenza virus infection and influenza-related hospitalisation in infants under?six months, in England in the 2013/14 season. Seasonal influenza vaccination in pregnancy was 71% (95% CI: 24-89%) effective in preventing infant influenza virus infection and 64% (95% CI: 6-86%) effective in preventing infant influenza hospitalisation, and should be recommended in pregnancy. .