Influenza vaccine effectiveness in Spain 2013/14: subtype-specific early estimates using the cycEVA study

S Jiménez-Jorge; F Pozo; S de Mateo; C Delgado-Sanz; I Casas; M García-Cenoz; J Castilla; R Sancho; L Etxebarriarteun-Aranzabal; C Quiñones; E Martínez; T Vega; A Garcia; J Giménez; J M Vanrell; D Castrillejo; A Larrauri; on behalf of Spanish Influenza Sentinel Surveillance System (SISS)

doi:10.2807/1560-7917.ES2014.19.9.20727

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Influenza vaccine effectiveness in Spain 2013/14: subtype-specific early estimates using the cycEVA study
S Jiménez-Jorge^1,2 , F Pozo³ , S de Mateo^1,2 , C Delgado-Sanz^1,2 , I Casas³ , M García-Cenoz^2,4 , J Castilla^2,4 , R Sancho^2,5 , L Etxebarriarteun-Aranzabal⁶ , C Quiñones⁷ , E Martínez⁷ , T Vega⁸ , A Garcia⁸ , J Giménez⁹ , J M Vanrell⁹ , D Castrillejo¹⁰ , A Larrauri^1,2 , on behalf of Spanish Influenza Sentinel Surveillance System (SISS)¹¹
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Affiliations: ¹ National Centre of Epidemiology, Institute of Health Carlos III, Madrid, Spain ² CIBER Epidemiología y Salud Pública (CIBERESP), Institute of Health Carlos III, Madrid, Spain ³ National Centre for Microbiology, National Influenza Reference Laboratory, WHO National Influenza Centre, Institute of Health Carlos III, Madrid, Spain ⁴ Instituto de Salud Pública de Navarra, Pamplona, Spain ⁵ Dirección de Salud Pública y Adicciones de Gipuzkoa, País Vasco, Spain ⁶ Subdirección de Salud Pública y Adicciones de Araba/Álava, País Vasco, Spain ⁷ Servicio de Epidemiología y Prevención Sanitaria, Dirección General de Salud Pública y Consumo de La Rioja, La Rioja, Spain ⁸ Dirección General de Salud Pública, Consejería de Sanidad de Castilla y León, Castilla y León, Spain ⁹ Servicio de Epidemiología, Dirección General de Salut Pública, Baleares, Spain ¹⁰ Servicio de Epidemiología, Dirección General de Sanidad y Consumo, Consejería de Bienestar Social y Sanidad, Ciudad Autónoma de Melilla, Melilla, Spain ¹¹ The members are listed at the end of the article

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S Jiménez-Jorge
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Citation style for this article: Jiménez-Jorge S, Pozo F, de Mateo S, Delgado-Sanz C, Casas I, García-Cenoz M, Castilla J, Sancho R, Etxebarriarteun-Aranzabal L, Quiñones C, Martínez E, Vega T, Garcia A, Giménez J, Vanrell J M, Castrillejo D, Larrauri A, on behalf of Spanish Influenza Sentinel Surveillance System (SISS). Influenza vaccine effectiveness in Spain 2013/14: subtype-specific early estimates using the cycEVA study. Euro Surveill. 2014;19(9):pii=20727. https://doi.org/10.2807/1560-7917.ES2014.19.9.20727 Received: 14 Feb 2014

Abstract

Adjusted early estimates of the 2013/14 influenza vaccine effectiveness (VE) in Spain for all age groups was 35% (95% CI: ?9 to 62), 33% (95% CI: ?33 to 67) and 28% (95% CI: ?33 to 61) against any influenza virus type, A(H1N1)pdm09 and A(H3N2) viruses, respectively. For the population targeted for vaccination, the adjusted VE was 44% (95% CI: ?11 to 72), 36% (95% CI: ?64 to 75) and 42% (95% CI: ?29 to 74), respectively. These preliminary results in Spain suggest a suboptimal protective effect of the vaccine against circulating influenza viruses.