Possible pandemic threat from new reassortment of influenza A(H7N9) virus in China

Z Meng; R Han; Y Hu; Z Yuan; S Jiang; X Zhang; J Xu

doi:10.2807/1560-7917.ES2014.19.6.20699

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Possible pandemic threat from new reassortment of influenza A(H7N9) virus in China
Z Meng¹ , R Han² , Y Hu¹ , Z Yuan¹ , S Jiang¹ , X Zhang^1,3 , J Xu^1,3
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Affiliations: ¹ Shanghai Public Health Clinical Center and Institutes of Biomedical Sciences, Key Laboratory of Medical Molecular Virology of Ministry of Education/Health, Shanghai Medical College, Fudan University, Shanghai, China ² Department of Cell and Molecular Physiology, Loyola University Chicago Health Sciences Division, Maywood, IL, United States ³ State Key Laboratory for Infectious Disease Prevention and Control, China Center for Disease Control and Prevention, Beijing, China

Correspondence:
J Xu
jianqingxu2008 gmail.com
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Citation style for this article: Meng Z, Han R, Hu Y, Yuan Z, Jiang S, Zhang X, Xu J. Possible pandemic threat from new reassortment of influenza A(H7N9) virus in China. Euro Surveill. 2014;19(6):pii=20699. https://doi.org/10.2807/1560-7917.ES2014.19.6.20699 Received: 29 Jan 2014

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Abstract

Avian influenza A(H7N9) virus re-emerged in China in December 2013, after a decrease in the number of new cases during the preceding six months. Reassortment between influenza A(H7N9) and local H9N2 strains has spread from China's south-east coast to other regions. Three new reassortments of A(H7N9) virus were identified by phylogenetic analysis: between A(H7N9) and Zhejiang-derived strains, Guangdong/Hong Kong-derived strains or Hunan-derived A(H9N2) strains. Our findings suggest there is a possible risk that a pandemic could develop.