Household transmission of haemolytic uraemic syndrome associated with Escherichia coli O104:H4, south-western France, June 2011

B Aldabe; Y Delmas; G Gault; B Vendrely; B Llanas; M Charron; C Castor; N Ong; F X Weill; P Mariani-Kurkdjian; F Terrier; M Desjardin; J Simões; B Le Bihan; C Combe; P Rolland

doi:10.2807/ese.16.31.19934-en

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Household transmission of haemolytic uraemic syndrome associated with Escherichia coli O104:H4, south-western France, June 2011
B Aldabe^1,2 , Y Delmas^2,3 , G Gault¹ , B Vendrely³ , B Llanas³ , M Charron¹ , C Castor¹ , N Ong¹ , F X Weill⁴ , P Mariani-Kurkdjian ⁵ , F Terrier⁶ , M Desjardin⁶ , J Simões⁷ , B Le Bihan⁷ , C Combe^3,8 , P Rolland^1,8
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Affiliations: ¹ French Institute for Public Health Surveillance (Institut de Veille Sanitaire; InVS), Regional office ‘Cire Aquitaine’, Bordeaux, France ² These authors contributed equally to this work ³ Bordeaux University Hospital, Bordeaux, France ⁴ Institut Pasteur, National Reference Centre for Escherichia coli and Shigella, Paris, France ⁵ Robert Debré Hospital, Associated Laboratory to the National Reference Centre for Escherichia coli and Shigella, Paris, France ⁶ Robert Picqué Military Hospital, Villenave-D’Ornon, France ⁷ Regional Health Agency of Aquitaine, Bordeaux, France ⁸ Both authors contributed equally to this work

Correspondence:
P Rolland
Patrick.ROLLAND ars.sante.fr
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Citation style for this article: Aldabe B, Delmas Y, Gault G , Vendrely B , Llanas B, Charron M, Castor C, Ong N, Weill F X, Mariani-Kurkdjian P, Terrier F, Desjardin M, Simões J, Le Bihan B, Combe C, Rolland P. Household transmission of haemolytic uraemic syndrome associated with Escherichia coli O104:H4, south-western France, June 2011. Euro Surveill. 2011;16(31):pii=19934. https://doi.org/10.2807/ese.16.31.19934-en Received: 29 Jul 2011

Abstract

Following the outbreak of haemolytic uraemic syndrome (HUS) on June 2011 in south-western France, household transmission due to Escherichia coli O104:H4 was suspected for two cases who developed symptoms 9 and 10 days after onset of symptoms of the index case. The analysis of exposures and of the incubation period is in favour of a secondary transmission within the family. Recommendations should be reinforced to prevent person-to-person transmission within households.