Early estimates of seasonal influenza vaccine effectiveness in Europe, 2010/11: I-MOVE, a multicentre case–control study

E Kissling; M Valenciano; Collective I-MOVE case–control studies team

doi:10.2807/ese.16.11.19818-en

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Early estimates of seasonal influenza vaccine effectiveness in Europe, 2010/11: I-MOVE, a multicentre case–control study
E Kissling¹ , M Valenciano¹ , Collective I-MOVE case–control studies team²
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Affiliations: ¹ EpiConcept, Paris, France ² Members of the team are listed at the end of the article

Correspondence:
E Kissling
e.kissling epiconcept.fr
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Citation style for this article: Kissling E, Valenciano M, I-MOVE case–control studies team Collective. Early estimates of seasonal influenza vaccine effectiveness in Europe, 2010/11: I-MOVE, a multicentre case–control study. Euro Surveill. 2011;16(11):pii=19818. https://doi.org/10.2807/ese.16.11.19818-en Received: 11 Mar 2011

Abstract

We present early estimates (up to week 4 of 2011) of the 2010/11 seasonal influenza vaccine effectiveness in preventing medically attended influenza-like illness (ILI) laboratory confirmed as influenza. Practitioners from seven European sentinel networks systematically swabbed ILI patients. We included patients meeting the European Union ILI case definition and swabbed less than eight days after symptom onset. Laboratory-confirmed influenza cases were compared with negative controls. The adjusted vaccine effectiveness was 42.3% (95% CI: -7.3 to 69.0%), suggesting moderate protection of the seasonal vaccine.