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Home Eurosurveillance Edition  2017: Volume 22/ Issue 26 Article 7
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Eurosurveillance, Volume 22, Issue 26, 29 June 2017
Addendum
Eurosurveillance editorial team: Addendum for Euro Surveill. 2017; 22(5)

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Citation style for this article: Eurosurveillance editorial team. Addendum for Euro Surveill. 2017; 22(5). Euro Surveill. 2017;22(26):pii=30564. DOI: http://dx.doi.org/10.2807/1560-7917.ES.2017.22.26.30564

Received:29 June 2017; Accepted:29 June 2017

In the article Emergence of the lymphogranuloma venereum l2c genovariant, Hungary, 2012 to 2016 by F Petrovay et al., published on 02 February 2017, the addendum shown below was added on 29 June 2017, at the request of the authors.

The predominating Chlamydia trachomatis strains causing lymphogranuloma venereum (LGV) described in the article, were initially identified as L2c genovariants. They were further investigated by the LGV Genotype Dynamics Study Group at the University Hospital Basel. Analyses showed the strains possess an L2 ompA-genotype (identical to accession number AM884176), and L2b pmpH-genotype [1]. Thus they share features with new variants of LGV described recently [2]. The majority of Hungarian LGV isolates appear to be this new genovariant. Based on ompA sequence analysis alone, one cannot reliably distinguish the classic and the novel L2 strains. Currently there is no distinguishing nomenclature for these strains.



References

  1. Verweij SP, Catsburg A, Ouburg S, Lombardi A, Heijmans R, Dutly F,  et al.  Lymphogranuloma venereum variant L2b-specific polymerase chain reaction: insertion used to close an epidemiological gap. Clin Microbiol Infect. 2011;17(11):1727-30. DOI: 10.1111/j.1469-0691.2011.03481.x PMID: 21895856

  2. Touati A, Peuchant O, Hénin N, Bébéar C, de Barbeyrac B. The L2b real-time PCR targeting the pmpH gene of Chlamydia trachomatis used for the diagnosis of lymphogranuloma venereum is not specific to L2b strains.Clin Microbiol Infect. 2016;22(6):574.e7-9. DOI: 10.1016/j.cmi.2016.03.018 PMID: 27040805



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